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Efficacy and side effects of beta 2-agonists by inhaled route in acute asthma in children: comparison of salbutamol, terbutaline, and fenoterol.

Author: NaspitzC K, ScalabrinD M, SoléD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Salbutamol, terbutaline, and fenoterol were equally effective in treating acute bronchospasm in children, but salbutamol was associated with more intense tremor and tachycardia.
Paper Details　
Original Abstract of the Article :
Thirty-seven separate episodes of acute bronchial asthma were studied in 21 asthmatic children. The bronchodilator, cardiovascular, and tremorigenic responses following administration of salbutamol (SAL), terbutaline (TER) and fenoterol (FEN) by closed-port intermittent nebulization were compared fo...See full text at original site
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引用元：
https://doi.org/10.3109/02770909609068185

データ提供：米国国立医学図書館（NLM）

Beta 2-Agonists for Acute Asthma in Children: Comparing Effectiveness and Side Effects

This study compares the effectiveness and side effects of three commonly used beta 2-agonists, salbutamol, terbutaline, and fenoterol, in treating acute asthma attacks in children. Think of a child experiencing a severe asthma attack, like a sudden sandstorm sweeping across the desert, making breathing difficult. This study, like a team of dedicated doctors, investigates the effectiveness of different medications to help clear the airways and alleviate the symptoms.

Beta 2-Agonists: Effective for Asthma Relief, But Varying Side Effects

The study found that all three beta 2-agonists were equally effective in treating acute asthma attacks in children. They worked quickly to open up the airways, allowing the children to breathe more easily. However, the study also observed that salbutamol, while effective, was associated with a higher incidence of tremor and tachycardia (increased heart rate). Terbutaline and fenoterol, like a gentler approach, had fewer of these side effects. This suggests that the choice of medication for treating acute asthma in children should be carefully considered, taking into account individual factors and the potential for side effects.

Navigating the Desert of Asthma: Choosing the Right Treatment

This study provides valuable insights into the use of beta 2-agonists in treating acute asthma in children. It's like having a team of doctors who are experts in navigating the desert of asthma, ready to provide the best possible care for each child.

Dr.Camel's Conclusion

This study highlights the effectiveness of beta 2-agonists in treating acute asthma attacks in children, but also emphasizes the importance of considering the potential for side effects. It's like having a caravan of medications, each with its own strengths and weaknesses, and it's important to choose the right one for the journey.

Date :
  1. Date Completed 1997-01-07
  2. Date Revised 2019-09-20
Further Info :

Pubmed ID

8968295

DOI: Digital Object Identifier

10.3109/02770909609068185

Related Literature

Article Analysis
・Side Effects of terbutaline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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