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Effect of regular terbutaline on the airway response to inhaled budesonide.

Author: BennettJ A, ClarkM M, OborneJ, TattersfieldA E, WildingP J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The study examines the effects of budesonide alone and in combination with regular terbutaline treatment on lung function, symptoms, and bronchial reactivity in asthmatic patients.
Paper Details　
Original Abstract of the Article :
The rebound increase in bronchial reactivity and fall in forced expiratory volume in one second (FEV1) following treatment with beta agonists seen in several studies has occurred regardless of concurrent steroid therapy. Little is known about the effect of adding beta agonists to corticosteroids, bu...See full text at original site
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引用元：
https://doi.org/10.1136/thx.51.10.989

データ提供：米国国立医学図書館（NLM）

Beta Agonists and Inhaled Corticosteroids: A Complex Relationship

Asthma is a common respiratory condition characterized by inflammation and narrowing of the airways. Inhaled corticosteroids are a mainstay treatment for asthma, but beta agonists, medications that relax the airways, are often used in conjunction with corticosteroids to provide rapid relief. This study examines the potential interactions between regular terbutaline, a beta agonist, and inhaled budesonide, a corticosteroid, on lung function, symptoms, and bronchial reactivity. The researchers sought to investigate the effects of combining these medications, looking for potential benefits and risks.

A Balancing Act: Navigating the Desert of Asthma Treatment

The study found that regular terbutaline treatment appeared to reduce some of the beneficial effects of inhaled budesonide, suggesting a potential interplay between these medications. It's like trying to maintain a delicate balance in a desert ecosystem, where the introduction of a new element can disrupt the delicate balance. The authors emphasize the need for further research to clarify the optimal use of beta agonists in conjunction with inhaled corticosteroids in the management of asthma.

Managing Asthma: A Personalized Approach to Treatment

This research highlights the importance of tailoring asthma treatment plans to the individual patient. It's like choosing the right tools for a journey through the desert, ensuring that they are appropriate for the specific conditions and challenges. By carefully considering the potential interactions between medications and individual patient needs, healthcare providers can optimize asthma treatment outcomes.

Dr.Camel's Conclusion

This research on the interaction between beta agonists and inhaled corticosteroids is like navigating a complex and ever-changing desert landscape. This study underscores the importance of understanding the subtle interplay between medications and individual patient needs, offering a roadmap for optimizing asthma treatment outcomes.

Date :
  1. Date Completed 1997-01-09
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

8977598

DOI: Digital Object Identifier

10.1136/thx.51.10.989

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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