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A comparison of 20 or 40 mg per day of carbimazole in the initial treatment of hyperthyroidism.

Author: HerbertM, HoptonM, JeffcoateW J, PageS R, SheardC E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the early clinical and biochemical responses to two different dosages of carbimazole (CBZ) for the treatment of hyperthyroidism.
Paper Details　
Original Abstract of the Article :
The optimal dosage regimen for carbimazole (CBZ) in the treatment of hyperthyroidism remains uncertain, despite clinical use of the drug for approximately fifty years. We have compared the early clinical and biochemical responses to 20 or 40 mg/day of CBZ given as initial treatment for hyperthyroidi...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2265.1996.00800.x

データ提供：米国国立医学図書館（NLM）

Finding the Right Dosage for Carbimazole: A Comparison of 20 mg vs. 40 mg Daily Doses in Hyperthyroidism

This study addresses the question of optimal dosage for carbimazole (CBZ), a medication commonly used to treat hyperthyroidism. The researchers compared the early clinical and biochemical responses to two different initial dosages of CBZ, 20 mg/day and 40 mg/day, in patients with hyperthyroidism.

Carbimazole Dosage: Finding the Right Balance

The study findings suggest that both 20 mg/day and 40 mg/day doses of CBZ are effective in controlling hyperthyroidism. However, the researchers observed differences in the rate of response between the two dosages, highlighting the importance of individualizing treatment based on patient needs and response.

Hyperthyroidism: Tailoring Treatment for Optimal Results

This study emphasizes the importance of individualized treatment for hyperthyroidism. The research findings suggest that the optimal dosage of CBZ may vary depending on patient factors. Careful monitoring of thyroid function and adjustments in dosage are essential to achieve optimal treatment outcomes.

Dr. Camel's Conclusion

Just like a camel adapting to different desert environments, hyperthyroidism treatment requires careful consideration of individual patient needs. This study sheds light on the importance of finding the right balance in CBZ dosage, emphasizing the need for personalized approaches in managing hyperthyroidism.

Date :
  1. Date Completed 1997-01-10
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

8977745

DOI: Digital Object Identifier

10.1046/j.1365-2265.1996.00800.x

Related Literature

Article Analysis
・Effective treatment of hyperthyroidism
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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