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Intravenous dolasetron for the prevention of postoperative nausea and vomiting after outpatient laparoscopic gynecologic surgery.

Author: BrownR A, GraczykS G, HahneW F, HickokC B, KallarS, McKenzieR, MelsonT, MorrillB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Dolasetron mesylate salt was effective and well tolerated for the prevention of PONV resulting from laparoscopic gynecologic surgery.
Paper Details　
Original Abstract of the Article :
The newer 5-hydroxytryptamine type 3 (5-HT3) antagonists are sometimes considered for routine prophylaxis of postoperative nausea and vomiting (PONV) in high-risk patients. This multicenter, randomized, double-blind, placebo-controlled study compared the efficacy and safety of three single intraveno...See full text at original site
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引用元：
https://doi.org/10.1097/00000539-199702000-00015

データ提供：米国国立医学図書館（NLM）

Preventing Postoperative Nausea and Vomiting: The Role of Dolasetron

This research examines the efficacy and safety of dolasetron, a 5-hydroxytryptamine type 3 (5-HT3) antagonist, in preventing postoperative nausea and vomiting (PONV) in patients undergoing outpatient laparoscopic gynecologic surgery. The study aimed to assess the effectiveness of different doses of dolasetron administered intravenously in reducing the incidence and severity of PONV. The authors highlight the significant impact of PONV on patient recovery and satisfaction.

Dolasetron's Effectiveness: Reducing Nausea and Vomiting

The study demonstrates that dolasetron significantly reduced the incidence and severity of PONV in patients undergoing laparoscopic gynecologic surgery. The authors found that all three doses of dolasetron were effective, with higher doses associated with a greater proportion of patients experiencing complete relief from PONV. They also found that dolasetron was well-tolerated, with a low incidence of adverse events.

A Valuable Tool for Postoperative Recovery: Minimizing Discomfort

This research provides valuable insights into the use of dolasetron as a preventive measure for PONV. The study's findings support the use of dolasetron as a safe and effective treatment option, potentially enhancing patient recovery and satisfaction after laparoscopic gynecologic surgery.

Dr.Camel's Conclusion

This research is like a camel caravan traveling through a desert oasis, where a refreshing drink of dolasetron can help prevent the unpleasant side effects of a long journey. The study's findings suggest that dolasetron can make the postoperative recovery experience more comfortable and enjoyable for patients. This research reminds us that the journey towards good health can be made smoother with the right tools and interventions.
Date :
  1. Date Completed 1997-03-04
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

9024022

DOI: Digital Object Identifier

10.1097/00000539-199702000-00015

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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