Studies on the effect and mode of action of flavoxate in human urinary bladder and sphincter.

Author: PedersenE

Paper Details 
Original Abstract of the Article :
Flavoxate, a smooth muscle relaxant, compared with propantheline showed no significant difference in clinical effect on voiding disturbances in hyperactive neurogenic bladders, but fewer side effects. Both drugs increased bladder capacity significantly, but flavoxate did not increase residual urine ...See full text at original site
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引用元:
https://doi.org/10.1159/000280131

データ提供:米国国立医学図書館(NLM)

Flavoxate: A Smooth Operator for Urinary Troubles

This study in the field of urology compares the efficacy and safety of flavoxate, a smooth muscle relaxant, to propantheline in treating voiding disturbances in hyperactive neurogenic bladders. The researchers aimed to evaluate the clinical effects of both medications and identify any potential differences in their side effect profiles.

Easing Bladder Woes

The study found that both flavoxate and propantheline effectively increased bladder capacity. However, flavoxate showed a significant advantage in terms of side effects. While both drugs were effective in reducing bladder problems, flavoxate was associated with fewer adverse effects. Notably, flavoxate did not increase residual urine, unlike propantheline.

Navigating Bladder Health

This study suggests that flavoxate may be a more favorable treatment option for hyperactive neurogenic bladders, as it offers a similar level of efficacy with fewer side effects. This research underscores the need for careful consideration of both efficacy and safety when choosing a treatment for bladder problems.

Dr.Camel's Conclusion

This study provides valuable insights into the comparative efficacy and safety of flavoxate and propantheline in treating voiding disturbances. The findings suggest that flavoxate, with its lower incidence of side effects and its ability to maintain bladder function without increasing residual urine, may be a preferable treatment option for hyperactive neurogenic bladders. This research highlights the importance of selecting medications based not only on their effectiveness but also on their potential side effects, thereby optimizing patient outcomes and improving quality of life.

Date :
  1. Date Completed 1977-11-25
  2. Date Revised 2018-02-17
Further Info :

Pubmed ID

906183

DOI: Digital Object Identifier

10.1159/000280131

SNS
PICO Info
in preparation
Languages

English

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