Effect of androgen deprivation therapy on local symptoms and tumour progression in men with metastatic carcinoma of the prostate.

Author: AbbouC C, JanknegtR A, SmithJ A, de GeryA

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate and compare the effects of medical or surgical castration combined with either nilutamide (Anandron) or placebo on symptoms of local tumour progression in men with carcinoma of the prostate. METHODS: The results from twin, randomised, prospective, placebo-controlled trials we...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1159/000474557

データ提供:米国国立医学図書館(NLM)

Androgen Deprivation Therapy: A Desert Oasis for Prostate Cancer

Prostate cancer, like a stubborn desert weed, can be difficult to control. This study, like a skilled gardener tending to a delicate ecosystem, investigates the effects of androgen deprivation therapy on local symptoms and tumor progression in men with metastatic prostate cancer. This study, like a careful scientist conducting a controlled experiment, examines the impact of medical or surgical castration combined with either nilutamide or placebo on tumor growth and urinary symptoms.

Androgen Deprivation Therapy: A Powerful Weapon Against Prostate Cancer

The researchers, like skilled desert explorers, meticulously analyzed data from 434 patients in each treatment group, observing significant improvements in urinary obstructive symptoms and a decrease in prostate volume in both groups. These findings, like a refreshing oasis in the harsh desert of prostate cancer, suggest that androgen deprivation therapy can effectively manage local symptoms and slow tumor progression. This study, like a detailed map guiding clinicians, highlights the benefits of androgen deprivation therapy for men with metastatic prostate cancer, providing a valuable tool for managing the disease.

Navigating the Desert of Prostate Cancer: Choosing the Right Path

This research, like a compass guiding patients through a challenging journey, underscores the importance of considering androgen deprivation therapy as a treatment option for metastatic prostate cancer. While the study highlights the effectiveness of androgen deprivation therapy, it also emphasizes the need for careful monitoring for side effects and potential long-term consequences. This study, like a reminder to travelers in the desert to pack wisely, encourages a comprehensive approach to prostate cancer treatment that involves a thorough evaluation of risks and benefits, personalized treatment plans, and ongoing monitoring for optimal outcomes.

Dr.Camel's Conclusion

This study demonstrates the effectiveness of androgen deprivation therapy in managing local symptoms and tumor progression in men with metastatic prostate cancer. However, it also emphasizes the importance of considering potential side effects and long-term consequences, advocating for personalized treatment plans and ongoing monitoring for optimal outcomes.

Date :
  1. Date Completed 1997-06-23
  2. Date Revised 2019-08-26
Further Info :

Pubmed ID

9101212

DOI: Digital Object Identifier

10.1159/000474557

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.