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The effects of famotidine, ranitidine and magnesium hydroxide/aluminium hydroxide on gastric fluid pH in adult horses.

Author: GrodinskyC, MurrayM J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Famotidine, ranitidine, and antacid were compared for their ability to increase gastric fluid pH in horses. Both famotidine and ranitidine were more effective than antacid in increasing gastric fluid pH. Ranitidine tended to increase gastric fluid pH greater than 6 longer than famotidine.
Paper Details　
Original Abstract of the Article :
Gastric fluid pH was measured in five adult horses following nasogastric administration of famotidine, 0.5, 1.0, and 2.0 mg/kg bodyweight (bwt); ranitidine, 4.4 and 6.6 mg/kg bwt and an antacid containing magnesium hydroxide (40 mg/ml) and aluminium hydroxide (45 mg/ml), 120 and 180 ml. Fluid was as...See full text at original site
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引用元：
https://doi.org/10.1111/j.2042-3306.1992.tb04773.x

データ提供：米国国立医学図書館（NLM）

Famotidine, Ranitidine, and Antacids: A Comparative Study of Gastric Fluid pH in Horses

In the world of animal health, understanding the intricacies of digestive processes is essential. This research investigates the effects of famotidine, ranitidine, and magnesium hydroxide/aluminum hydroxide on gastric fluid pH in horses. The study explores the potential of these medications to modify gastric acidity and potentially mitigate digestive issues in these magnificent creatures.

A Comparative Analysis: Finding the Right Solution for Digestive Health

The study reveals that both famotidine and ranitidine effectively increase gastric fluid pH in horses, but the antacid had a more variable and short-lived effect. This finding suggests that famotidine and ranitidine may be more reliable options for managing gastric acidity in horses, potentially leading to improved digestive health.

Optimizing Digestive Health in Horses: A Journey of Discovery

This research provides valuable insights into the effects of different medications on gastric fluid pH in horses. It highlights the importance of considering the individual needs of each horse and selecting the most appropriate treatment approach to optimize digestive health. Remember, just as a camel's digestive system is adapted to thrive in the desert's harsh conditions, we must respect the unique physiology of horses and provide tailored care to support their well-being.

Dr. Camel's Conclusion

The digestive system, like a camel's hump, is a marvel of adaptation and resilience. This study explores the potential of various medications to influence gastric fluid pH in horses, providing valuable information for veterinarians seeking to optimize digestive health in these magnificent creatures. Remember, just as a wise camel traveler carries essential supplies for a long journey, vets must be equipped with the knowledge and tools to effectively manage the digestive health of their equine patients.

Date :
  1. Date Completed 1997-05-15
  2. Date Revised 2019-11-02
Further Info :

Pubmed ID

9109961

DOI: Digital Object Identifier

10.1111/j.2042-3306.1992.tb04773.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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