Paper Details 
Original Abstract of the Article :
The objective of this study was to use the technique of meta-analysis to undertake a systematic review of published and unpublished randomized controlled trials of pharmacological agents to determine their relative efficacy and toxicity in the treatment of psoriatic arthritis. The main outcome measu...See full text at original site
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引用元:
https://doi.org/10.1093/rheumatology/36.1.95

データ提供:米国国立医学図書館(NLM)

Psoriatic Arthritis: A Quantitative Oasis in the Desert of Treatment Options

Psoriatic arthritis, a chronic inflammatory condition, is a challenging disease to manage, often requiring a multifaceted approach. This research aims to provide a quantitative overview of the therapeutic options for psoriatic arthritis, evaluating the relative efficacy and toxicity of various pharmacological agents.

Through a systematic review and meta-analysis of published and unpublished randomized controlled trials, the researchers found that while all agents were better than placebo, parenteral high-dose methotrexate and salazopyrin emerged as the most effective treatments for psoriatic arthritis. The study also highlighted the need for further research to determine the efficacy of other agents, such as etretinate, oral low-dose methotrexate, azathioprine, and colchicine. This research serves as a valuable guide for navigating the complex landscape of psoriatic arthritis treatment options.

A Guide Through the Desert: Navigating Psoriatic Arthritis Treatment

The study's findings offer valuable insights into the treatment of psoriatic arthritis. The researchers' meta-analysis provides a quantitative framework for comparing the efficacy of different pharmacological agents, offering clinicians a more informed basis for making treatment decisions. This research underscores the importance of evidence-based medicine in guiding clinical practice.

Finding the Right Oasis: A Call for Further Research

While the study provides a comprehensive overview of current treatment options, it also highlights the need for further research to fully evaluate the efficacy and safety of various agents. The researchers emphasize the importance of conducting larger and more comprehensive clinical trials to determine the optimal treatment strategies for individual patients. This research serves as a valuable call to action for the research community to continue exploring new and innovative treatments for psoriatic arthritis.

Dr.Camel's Conclusion

This research offers a valuable quantitative overview of the therapeutic options for psoriatic arthritis, providing a roadmap for navigating the complex landscape of treatment decisions. The findings highlight the need for ongoing research to fully evaluate the efficacy and safety of various agents, ultimately leading to better outcomes for individuals living with this chronic inflammatory condition.

Date :
  1. Date Completed 1997-04-22
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

9117186

DOI: Digital Object Identifier

10.1093/rheumatology/36.1.95

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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