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Intravenous dolasetron mesilate in the prevention of postoperative nausea and vomiting in females undergoing gynecological surgery.

Author: BrownR A, D'HollanderA, DiemunschP, HahneW F, NavéS, PaxtonL, SchoefflerP, WesselP

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Dolasetron mesilate was effective and well-tolerated in preventing post-operative nausea and vomiting (PONV) in women undergoing gynecologic surgery under general anesthesia.
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVE: To evaluate a range of doses of intravenous (i.v.) dolasetron mesilate, in preventing postoperative nausea and vomiting (PONV). DESIGN: Double-blind, placebo-controlled, randomized, multicenter trial. SETTING: Ten hospitals and/or surgical centers. PATIENTS: 281 women undergoing ...See full text at original site
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引用元：
https://doi.org/10.1016/s0952-8180(97)00063-9

データ提供：米国国立医学図書館（NLM）

Intravenous Dolasetron for Postoperative Nausea and Vomiting

Postoperative nausea and vomiting (PONV) is a common and often unpleasant side effect of surgery. This study investigates the effectiveness of intravenous (i.v.) dolasetron mesilate in preventing PONV in women undergoing gynecologic surgery. It's like discovering a new type of desert plant that can soothe the stomach and prevent discomfort.

The researchers conducted a randomized controlled trial, administering different doses of dolasetron mesilate to patients undergoing gynecologic surgery. They monitored the patients for 24 hours after surgery, assessing the incidence and severity of PONV. It's like observing the effects of a new type of desert herb on a group of travelers, measuring their reactions and well-being.

Dolasetron's Effectiveness in Preventing PONV

The study showed that dolasetron mesilate was effective in reducing PONV in women undergoing gynecologic surgery. It was well tolerated and did not cause significant adverse effects. It's like finding a hidden oasis that provides both relief from discomfort and nourishment for those who seek it.

Relief from Postoperative Discomfort

This research provides valuable insights into the potential of dolasetron mesilate for preventing PONV. It's like finding a new source of fresh water in a desert, providing relief and comfort for those who have been struggling with this common side effect of surgery.

Dr.Camel's Conclusion

This study provides strong evidence that dolasetron mesilate is an effective and well-tolerated treatment for preventing PONV in women undergoing gynecologic surgery. It's a welcome addition to the medical toolbox, providing a much-needed solution for a common and often debilitating side effect of surgery.

Date :
  1. Date Completed 1997-10-30
  2. Date Revised 2019-09-14
Further Info :

Pubmed ID

9257201

DOI: Digital Object Identifier

10.1016/s0952-8180(97)00063-9

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Languages

English

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