Paper Details 
Original Abstract of the Article :
The oral antidiabetics glibenclamide, glipizide, glymidine, tolazamide and tolbutamide and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, furosemide, hydrochlorothiazide, hydroflumethiazide and trichlormethiazide were investigated for phototoxic effec...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1600-0781.1997.tb00100.x

データ提供:米国国立医学図書館(NLM)

Sulfonamide-Derived Drugs: A Case of Sensitivity to Light

In the world of medicine, we are constantly seeking to understand the complex interactions between medications and the human body. This research, like a scientific investigation, explores the phototoxic effects of sulfonamide-derived drugs, a class of medications used to treat various conditions, including diabetes and high blood pressure. The researchers, like forensic scientists examining a crime scene, tested the effects of these drugs on hairless mice, exposing them to ultraviolet (UV) light. This study, like a carefully conducted experiment, reveals the potential for these drugs to cause skin reactions when exposed to light.

Light Sensitivity: A Hidden Threat

The study, like a detailed report, found that several sulfonamide-derived drugs, like a group of suspects in a mystery, induced skin reactions when exposed to UV light. This finding, like a clue revealing a hidden connection, suggests that these drugs could pose a risk to patients, particularly those who are sensitive to light. The researchers, like experienced detectives, have identified a potential danger associated with these medications, emphasizing the importance of caution when prescribing them to patients.

Sun Safety: A Word of Caution

This research, like a cautionary tale, highlights the importance of sun safety, especially for patients taking sulfonamide-derived medications. The researchers, like vigilant guardians, emphasize the need for sun protection, such as wearing sunscreen and avoiding prolonged exposure to sunlight, for those taking these drugs. This study, like a reminder to pack a hat and sunglasses before embarking on a desert journey, encourages a proactive approach to preventing potential harm from light sensitivity.

Dr.Camel's Conclusion

This study, like a journey through a sun-drenched desert, reveals the importance of understanding the potential side effects of medications. The researchers, like experienced desert guides, have identified a potential hazard associated with sulfonamide-derived drugs, reminding us to be cautious and mindful of our exposure to light. This research, like a beacon warning of hidden dangers, encourages us to protect ourselves from the harmful effects of sunlight, especially when taking these medications.

Date :
  1. Date Completed 1998-01-12
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

9361121

DOI: Digital Object Identifier

10.1111/j.1600-0781.1997.tb00100.x

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