Paper Details 
Original Abstract of the Article :
Cyclosporine (CsA) is frequently used for nontransplant indications such as autoimmune diseases. Unfortunately, side effects such as renal dysfunction and hypertension are frequently described in spite of close monitoring with CsA trough levels. The purpose of the present prospective cohort study wa...See full text at original site
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引用元:
https://doi.org/10.1159/000169140

データ提供:米国国立医学図書館(NLM)

Cyclosporine Dose Adjustment: A Balancing Act in the Desert

The management of autoimmune diseases is a delicate balancing act, much like traversing a shifting desert landscape. This prospective cohort study explores the use of cyclosporine (CsA) levels obtained 6 hours after the morning dose (T6) for dose adjustment in patients with autoimmune diseases. The study aims to assess the impact of this approach on the incidence of CsA-related side effects, such as renal dysfunction and hypertension. The researchers meticulously monitor patients for changes in blood pressure, biochemical parameters, and CsA levels, carefully navigating the potential risks and benefits of different treatment strategies.

A New Approach to Cyclosporine Management

The study suggests that dose adjustment based on T6 levels may allow for lower CsA doses, potentially reducing the incidence of side effects while maintaining therapeutic efficacy. These findings hold promise for improving the management of autoimmune diseases, offering a more personalized and patient-centered approach.

A Glimpse into the Future of Autoimmune Treatment

This study provides a glimpse into the future of autoimmune disease management, highlighting the importance of personalized medicine and individualized treatment strategies. By leveraging the power of monitoring and adjusting medication doses based on individual patient needs, we can strive to improve patient outcomes and minimize the burden of disease.

Dr.Camel's Conclusion

This study presents a novel approach to cyclosporine management in patients with autoimmune diseases, suggesting that dose adjustment based on T6 levels may reduce the incidence of side effects. This research underscores the importance of personalized medicine and highlights the potential for improved patient outcomes through tailored treatment strategies.

Date :
  1. Date Completed 1997-11-10
  2. Date Revised 2018-02-15
Further Info :

Pubmed ID

9382165

DOI: Digital Object Identifier

10.1159/000169140

Related Literature

SNS
PICO Info
in preparation
Languages

English

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