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Original Abstract of the Article :
Cyclosporine (CsA) is frequently used for nontransplant indications such as autoimmune diseases. Unfortunately, side effects such as renal dysfunction and hypertension are frequently described in spite of close monitoring with CsA trough levels. The purpose of the present prospective cohort study wa...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000169140
データ提供:米国国立医学図書館(NLM)
Cyclosporine Dose Adjustment: A Balancing Act in the Desert
The management of autoimmune diseases is a delicate balancing act, much like traversing a shifting desert landscape. This prospective cohort study explores the use of cyclosporine (CsA) levels obtained 6 hours after the morning dose (T6) for dose adjustment in patients with autoimmune diseases. The study aims to assess the impact of this approach on the incidence of CsA-related side effects, such as renal dysfunction and hypertension. The researchers meticulously monitor patients for changes in blood pressure, biochemical parameters, and CsA levels, carefully navigating the potential risks and benefits of different treatment strategies.
A New Approach to Cyclosporine Management
The study suggests that dose adjustment based on T6 levels may allow for lower CsA doses, potentially reducing the incidence of side effects while maintaining therapeutic efficacy. These findings hold promise for improving the management of autoimmune diseases, offering a more personalized and patient-centered approach.
A Glimpse into the Future of Autoimmune Treatment
This study provides a glimpse into the future of autoimmune disease management, highlighting the importance of personalized medicine and individualized treatment strategies. By leveraging the power of monitoring and adjusting medication doses based on individual patient needs, we can strive to improve patient outcomes and minimize the burden of disease.
Dr.Camel's Conclusion
This study presents a novel approach to cyclosporine management in patients with autoimmune diseases, suggesting that dose adjustment based on T6 levels may reduce the incidence of side effects. This research underscores the importance of personalized medicine and highlights the potential for improved patient outcomes through tailored treatment strategies.
Date :
- Date Completed 1997-11-10
- Date Revised 2018-02-15
Further Info :
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