Triazolam impairs delayed recall but not acquisition of various everyday memory tasks in humans.

Author: AbdelnabyM, Ambros-IngersonJ, DavisC M, GrangerR, LynchG, WuJ, ZabanehR

Paper Details 
Original Abstract of the Article :
A double-blind test battery was administered to 24 human subjects (8 control, 16 drug) to assess the effects of 0.125 mg triazolam (oral) on memory encoding and retention across delay intervals ranging from seconds to 1 week after presentation. Although the drug reduced immediate psychomotor perform...See full text at original site
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引用元:
https://doi.org/10.1006/exnr.1997.6631

データ提供:米国国立医学図書館(NLM)

Triazolam's Impact on Everyday Memory

The field of [memory research] is an endless desert of fascinating complexities. This study, like a trusty camel navigating the dunes, dives deep into the effects of [triazolam] on human memory. The researchers, armed with a double-blind test battery, embarked on a journey to understand how this drug affects memory encoding and retention over different timeframes, ranging from seconds to a week. They discovered that while triazolam may slow down immediate psychomotor performance, it doesn't significantly hinder the recall of previously learned information or the encoding of new information. Interestingly, the drug enhanced immediate recall of playing card location and identity, but this effect disappeared after four hours. The study also revealed that triazolam impaired the recall of object names, particularly after 20 minutes, 4 hours, and even after a day or a week. These memory impairments are consistent with the known effects of triazolam on [long-term potentiation], a crucial process involved in memory formation and expression.

Unveiling Triazolam's Memory Impact

This research sheds light on the specific ways in which triazolam affects memory. The findings suggest that triazolam doesn't completely erase memories, but rather disrupts their accessibility over time. This is akin to having a treasure map, but the markings fade as time passes, making it increasingly difficult to find the treasure. The study's results provide valuable insights into the intricate relationship between drugs and memory function, offering a glimpse into the vast desert of knowledge that is human cognition.

Triazolam's Influence on Everyday Life

If you're taking triazolam, it's important to be aware of its potential impact on your memory, particularly for tasks requiring remembering details over time. This could range from remembering appointments to recalling important conversations. It's wise to keep a diary or use reminders to compensate for any memory difficulties. However, it's crucial to remember that this study focused on a specific dosage of triazolam, and the effects may vary depending on individual factors.

Dr.Camel's Conclusion

This research offers a valuable glimpse into the effects of triazolam on memory, highlighting its impact on retrieving information over time. It's a reminder that even seemingly small changes in brain chemistry can have significant consequences for our ability to navigate the vast desert of our own memories. This study encourages us to be mindful of how our choices can affect our cognitive abilities and to seek guidance from healthcare professionals when needed.

Date :
  1. Date Completed 1998-01-07
  2. Date Revised 2019-12-11
Further Info :

Pubmed ID

9398455

DOI: Digital Object Identifier

10.1006/exnr.1997.6631

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English

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