An overview of the influence of ACE inhibitors on fetal-placental circulation and perinatal development.

Author: ButtarH S

Paper Details 
Original Abstract of the Article :
The renin-angiotensin system is associated with a variety of pathophysiological processes in many organ systems, and is known to be involved in the normal regulation of blood pressure and in the pathogenesis of renovascular hypertension. Angiotensin II is a multifunctional hormone that manifests its...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/9406146

データ提供:米国国立医学図書館(NLM)

The Renin-Angiotensin System and Pregnancy: A Balancing Act

This research dives deep into the fascinating world of [pharmacology] and its impact on pregnancy. The renin-angiotensin system, which regulates blood pressure, is like a delicate balancing act in the body. ACE inhibitors, a class of drugs used to manage hypertension and heart disease, can disrupt this balance, especially during pregnancy. This study investigates the potential risks of ACE inhibitors on fetal development, using both human and animal models. The authors found that ACE inhibitors can lead to a range of complications like oligohydramnios, renal tubular dysgenesis, and even fetal death.

ACE Inhibitors: A Double-Edged Sword?

These findings highlight the potential risks of using ACE inhibitors during pregnancy. The study shows that these drugs can have a direct impact on the fetal renin-angiotensin system, potentially leading to complications. This finding is particularly relevant as ACE inhibitors are often prescribed to pregnant women with hypertension, making it crucial for healthcare professionals to carefully weigh the risks and benefits of these medications.

Navigating Pregnancy with ACE Inhibitors

As a future mom-to-be, you might be wondering about the safety of ACE inhibitors during pregnancy. This research suggests that ACE inhibitors can pose potential risks to the developing fetus. It's important to discuss your medical history and medication needs with your doctor to ensure the safest possible outcome for both you and your baby.

Dr. Camel's Conclusion

Remember, pregnancy is a unique and delicate journey. It's essential to be well-informed and work closely with your healthcare provider to make informed decisions about your medications and overall care. Just like a camel navigating a vast desert, pregnancy requires careful attention to detail and a thoughtful approach to ensure a smooth and healthy journey.

Date :
  1. Date Completed 1998-01-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

9406146

DOI: Digital Object Identifier

9406146

Related Literature

SNS
PICO Info
in preparation
Languages

English

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