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The efficacy and safety of one-week triple therapy with lansoprazole, clarithromycin, and metronidazole for the treatment of Helicobacter pylori infection in Japanese patients.

Author: IdoK, KihiraK, KimuraK, SaifukuK, SatohK, SekiM, TakimotoT, TaniguchiY, YoshidaY

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A 1-week, low-dose triple therapy with lansoprazole, clarithromycin, and metronidazole (LCM1) was highly effective and safe for Japanese patients with H. pylori infection, achieving a 92.3% cure rate.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The aim of this study was to evaluate the efficacy and tolerability of 1-week, low-dose triple therapy with lansoprazole, clarithromycin, and metronidazole (LCM) for the cure of H. pylori infection and to establish the adequate dosage of a new triple therapy for Japanese patients. MATER...See full text at original site
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引用元：
https://doi.org/10.1111/j.1523-5378.1997.tb00064.x

データ提供：米国国立医学図書館（NLM）

Helicobacter pylori: One-Week Triple Therapy for Eradication

Helicobacter pylori, a stealthy bacterium that can infect the stomach, is a common cause of gastritis and ulcers. This study focused on a one-week triple therapy regimen, combining lansoprazole, clarithromycin, and metronidazole, for the eradication of Helicobacter pylori in Japanese patients. The researchers conducted a study, where participants received either a standard or a higher dose of metronidazole, to assess the efficacy and safety of this treatment approach. They found that both regimens were highly effective in eradicating Helicobacter pylori, with a cure rate of over 90% in both groups. The regimens were also well-tolerated, with minimal side effects reported.

The Takeaway: One-Week Triple Therapy Shows Success in Eradicating Helicobacter pylori

This study demonstrates the effectiveness of one-week triple therapy in eradicating Helicobacter pylori infection. The regimen, combining lansoprazole, clarithromycin, and metronidazole, offers a promising approach to treating Helicobacter pylori infection, potentially reducing the risk of gastritis and ulcers.

The Impact on Your Health: Stomach Health and Helicobacter pylori

If you are experiencing stomach discomfort, it's important to consult with your healthcare provider. They can perform tests to determine if you have Helicobacter pylori infection and recommend appropriate treatment options. Remember, early diagnosis and treatment can help prevent complications and improve your overall health.

Dr. Camel's Conclusion

This study highlights the importance of finding effective and efficient treatment options for common infections. The one-week triple therapy regimen for Helicobacter pylori eradication offers a promising approach, potentially reducing the burden of this infection. Remember, taking care of your stomach health, like tending to a precious oasis in a vast desert, is essential for overall well-being.

Date :
  1. Date Completed 1998-01-14
  2. Date Revised 2019-11-02
Further Info :

Pubmed ID

9432334

DOI: Digital Object Identifier

10.1111/j.1523-5378.1997.tb00064.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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