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Churg-Strauss syndrome associated with zafirlukast.

Author: CraigT J, FerrissJ, GroffJ, HollowayJ, KlinekM, KlinikM

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Zafirlukast, a leukotriene modifier, has been associated with Churg-Strauss syndrome, a rare vasculitis.
Paper Details　
Original Abstract of the Article :
In recent years, the leukotriene modifiers, a new class of drugs, have become commercially available as a promising medication for asthma. According to the 1997 National Institutes of Health guidelines, the leukotriene modifiers are indicated in mild persistent asthma as an alternative to inhaled st...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/9615559

データ提供：米国国立医学図書館（NLM）

Churg-Strauss Syndrome and Zafirlukast: A Desert Storm in Respiratory Health

Churg-Strauss syndrome (CSS) is a rare but serious inflammatory condition affecting blood vessels. This study investigates a potential link between CSS and the use of zafirlukast, a medication used to treat asthma.

The researchers report a case of CSS in a patient taking zafirlukast and discuss previously documented cases of this association. They emphasize the need for vigilance regarding the potential development of CSS in asthma patients taking zafirlukast, particularly those being weaned from oral corticosteroids. It’s like navigating a desert – while a new path may seem promising, it’s important to be aware of potential hazards and take precautions.

Navigating the Desert of Asthma Treatment: A Cautionary Tale

The study’s findings raise concerns about the potential for zafirlukast to trigger CSS in certain individuals. It’s like encountering a sandstorm in the desert – unexpected and potentially dangerous. While zafirlukast is generally considered safe for most patients, this study highlights the importance of careful monitoring and prompt intervention if any signs of CSS appear.

The Desert of Respiratory Health: A Need for Vigilance

This research underscores the importance of recognizing potential adverse effects of medications, particularly those related to respiratory health. It’s like exploring a desert – knowing the terrain and being prepared for unexpected challenges is crucial for safety. By being vigilant and working closely with healthcare providers, we can help ensure the well-being of patients with asthma.

Dr. Camel's Conclusion

This study serves as a reminder that even seemingly safe medications can have unforeseen side effects. It’s like venturing into a desert – while the journey may appear calm and peaceful, unexpected storms can erupt. By understanding the potential risks and maintaining vigilance, we can better manage asthma and protect the health of those affected by this condition.

Date :
  1. Date Completed 1998-07-02
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

9615559

DOI: Digital Object Identifier

9615559

Related Literature

Article Analysis
・Side Effects of zafirlukast
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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