Paper Details 
Original Abstract of the Article :
Antacids containing aluminum and magnesium hydroxide are widely used nonprescription agents for treatment of gastritis and peptic ulcer disease. One of the side effects of these antacids is that they bind phosphate in the gut, resulting in its malabsorption. Short-term use, consistent with the direc...See full text at original site
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引用元:
https://doi.org/10.1016/s8756-3282(98)00060-x

データ提供:米国国立医学図書館(NLM)

Antacids and Osteomalacia: A Case of Unintended Consequences

Antacids are commonly used to relieve heartburn and indigestion, but excessive use can lead to unexpected consequences. This case study explores the potential for long-term antacid use, even within recommended guidelines, to cause osteomalacia, a condition characterized by soft and weak bones. The researchers investigated the case of a patient who self-medicated with high doses of antacids, leading to significant phosphate depletion and bone aluminum accumulation.

The Hidden Risks of Antacid Overuse: A Cautionary Tale

The case study highlights the importance of being mindful of the potential risks associated with long-term use of antacids, even when taken within the recommended dosage. Excessive use can lead to significant phosphate depletion and bone mineral density loss, increasing the risk of developing osteomalacia.

Antacids and Bone Health: A Balancing Act

While antacids can be beneficial for managing occasional heartburn or indigestion, it's crucial to use them responsibly and avoid excessive or prolonged use. Consult with your doctor about the potential risks and benefits of antacids for your specific needs. Maintaining a balanced diet rich in calcium, vitamin D, and phosphorus can also contribute to overall bone health.

Dr. Camel's Conclusion

This case study serves as a reminder that even seemingly harmless medications can have unintended consequences when used excessively. It's essential to approach all medications with caution, be aware of potential side effects, and consult with your healthcare provider for personalized advice. Maintaining a healthy lifestyle and addressing any underlying medical conditions can help minimize the risk of complications associated with long-term antacid use.

Date :
  1. Date Completed 1998-10-22
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

9626411

DOI: Digital Object Identifier

10.1016/s8756-3282(98)00060-x

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SNS
PICO Info
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Languages

English

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