Hemodynamic effects of thiothixene and chlorpromazine in schizophrenic patients at rest and during exercise.

Author: CarlssonC, DenckerS J, GrimbyG, HäggendalJ, JohnssonG

Paper Details 
Original Abstract of the Article :
The hemodynamic effects and plasma levels of noradrenaline were studied in schizophrenic patients at rest and during exercise after long-term treatment with chlorpromazine (150-600 mg daily) and thiothixene (60-80 mg daily). The results are compared with those from previous studies in untreated pati...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/965133

データ提供:米国国立医学図書館(NLM)

Hemodynamic Effects of Antipsychotics: Exploring the Body's Desert

Imagine the human body as a vast desert, with intricate pathways and delicate balances. Antipsychotic medications are like travelers navigating these pathways, influencing the body's delicate balance. This research explores the hemodynamic effects of thiothixene and chlorpromazine, two commonly used antipsychotic medications, on schizophrenic patients. It's like studying how different travelers impact the desert's ecosystem, analyzing their influence on water sources and plant life. The researchers measured various hemodynamic parameters, such as heart rate and stroke volume, both at rest and during exercise, to assess the impact of these medications on cardiovascular function. This is like observing the effects of different travelers on the desert's delicate balance.

Antipsychotic Effects: A Complex Desert Journey

The study found that thiothixene had relatively moderate effects on hemodynamic variables, while chlorpromazine showed a tendency to increase heart rate and decrease stroke volume. This is like observing different travelers' impacts on the desert's ecosystem, with some having a more significant effect than others. The research also found that higher doses of chlorpromazine were associated with higher levels of noradrenaline, a neurotransmitter involved in stress response. This is like observing how different travelers' journeys through the desert can influence the availability of vital resources.

Navigating the Antipsychotic Landscape

This research provides valuable insights into the hemodynamic effects of antipsychotic medications. It highlights the need for careful monitoring and management of cardiovascular health in patients receiving these medications. This is like recognizing that navigating the desert's vast landscape requires careful planning and awareness of potential hazards.

Dr.Camel's Conclusion

This research reminds us that even the most effective medications can have complex effects on the body's intricate systems. It's a reminder that navigating the desert of mental health requires careful consideration of the potential impacts of medications on both the mind and the body. By understanding these effects, we can better guide patients through their journeys towards healing and well-being.

Date :
  1. Date Completed 1976-11-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

965133

DOI: Digital Object Identifier

965133

Related Literature

SNS
PICO Info
in preparation
Languages

English

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