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Immunotherapy of chronic hepatitis B by anti HBV vaccine.

Author: BerthelotP, BréchotC, CarnotF, CouillinI, DrissF, MichelM L, NalpasB, PolS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the potential of vaccine therapy for chronic hepatitis B virus (HBV) infection. The study found that vaccine therapy was effective in reducing or eliminating HBV DNA in a significant number of patients, with or without additional interferon treatment.
Paper Details　
Original Abstract of the Article :
Vaccine therapy is now used in various infectious diseases. The hepatitis B virus (HBV) leads to chronic infection in around 5% of patients with a high risk of chronic active hepatitis which may result in cirrhosis and hepatocellular carcinoma. The partial efficacy of antiviral therapies (40% of sus...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/9658616

データ提供：米国国立医学図書館（NLM）

Immunotherapy for Chronic Hepatitis B: A Promising Approach

Hepatitis B is a viral infection that can cause serious liver damage. Developing effective treatments for chronic hepatitis B has been a major focus of medical research. This study explores the potential of vaccine therapy as an immune-based approach for managing this condition.

The researchers investigated the effects of anti-HBV vaccine therapy in patients with chronic HBsAg carriers. They found that vaccine therapy led to a significant decrease in serum HBV DNA levels and, in some cases, complete elimination of the virus. The study suggests that vaccine therapy may be a viable alternative or adjunct to antiviral therapies for treating chronic hepatitis B.

Chronic Hepatitis B: A Journey Toward Control

This research provides a glimmer of hope for individuals living with chronic hepatitis B. It suggests that vaccine therapy could potentially play a significant role in managing this condition. The study emphasizes the importance of ongoing research to explore the full potential of immune-based approaches for treating chronic hepatitis B.

Living with Hepatitis B: A Pathway to Well-being

As a camel who has navigated challenging landscapes, I understand the importance of resilience and self-care. For individuals living with hepatitis B, maintaining a healthy lifestyle, following medical recommendations, and engaging in regular exercise can help manage the condition and improve overall well-being.

Dr. Camel's Conclusion

This study highlights the potential of vaccine therapy as a promising approach for treating chronic hepatitis B. It’s a reminder that medical research is continuously seeking new and innovative ways to combat viral infections and improve patient outcomes. This research inspires us to remain hopeful about the future of hepatitis B treatment.

Date :
  1. Date Completed 1998-08-21
  2. Date Revised 2016-09-23
Further Info :

Pubmed ID

9658616

DOI: Digital Object Identifier

9658616

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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