Treatment of uterine fibroids with a slow-release formulation of the gonadotrophin releasing hormone antagonist Cetrorelix.

Author: BauerO, ButtgeI, DiedrichK, EngelJ, FelberbaumR E, GermerU, HeiseS, LudwigM, ReissmannT, Riethmüller-WinzenH

Paper Details 
Original Abstract of the Article :
A depot preparation of the third-generation gonadotrophin-releasing hormone (GnRH) antagonist Cetrorelix (SB-75) was used for preoperative treatment in twenty premenopausal patients with symptomatic uterine fibroids who were to undergo surgery. In a prospective, open, randomized setting 60 mg of Cet...See full text at original site
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引用元:
https://doi.org/10.1093/humrep/13.6.1660

データ提供:米国国立医学図書館(NLM)

Treating Uterine Fibroids: A New Approach with Cetrorelix

Uterine fibroids, a common condition affecting women, can cause significant symptoms and discomfort. This study investigates the effectiveness of a slow-release formulation of the gonadotropin-releasing hormone (GnRH) antagonist Cetrorelix in treating premenopausal women with symptomatic uterine fibroids.

Cetrorelix: A Promising Therapy for Uterine Fibroids

The researchers conducted a prospective, open-label study involving 20 premenopausal women with uterine fibroids. The results demonstrated that Cetrorelix effectively suppressed gonadotropin and sex steroid secretion, leading to significant fibroid shrinkage. The study highlights the rapid reduction in fibroid size observed with Cetrorelix, suggesting its potential as a valuable pre-surgical treatment option.

Minimizing Fibroid Size: A Pathway to Improved Quality of Life

This research offers a promising new approach for managing uterine fibroids, providing a safe and effective treatment option that can minimize fibroid size and alleviate associated symptoms. The rapid fibroid shrinkage observed with Cetrorelix could significantly improve patient quality of life, reducing discomfort and facilitating surgical intervention.

Dr.Camel's Conclusion

Uterine fibroids can be a challenging condition for women, impacting their health and well-being. This study sheds light on the potential of Cetrorelix as a valuable pre-surgical treatment option, providing a safe and effective way to minimize fibroid size and improve patient outcomes. Just as a camel navigates the desert with resilience and adaptation, women facing uterine fibroids can now benefit from this promising therapy, offering a path to improved quality of life and reduced symptoms.

Date :
  1. Date Completed 1998-11-12
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

9688409

DOI: Digital Object Identifier

10.1093/humrep/13.6.1660

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PICO Info
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Languages

English

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