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Tramadol versus hydrocodone-acetaminophen in acute musculoskeletal pain: a randomized, double-blind clinical trial.

Author: LarkinG L, ParisP M, TurturroM A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Hydrocodone-acetaminophen provides superior analgesia to tramadol in ED patients with acute musculoskeletal pain.
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVE: To evaluate the efficacy of an oral tramadol preparation versus that of an oral hydrocodone-acetaminophen preparation in acute musculoskeletal pain. METHODS: A randomized, prospective, double-blind clinical trial was conducted in an urban teaching emergency department with an annua...See full text at original site
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引用元：
https://doi.org/10.1016/s0196-0644(98)70127-1

データ提供：米国国立医学図書館（NLM）

Tramadol vs. Hydrocodone-Acetaminophen: A Painful Debate in the Desert

The study delves into the world of pain relief, a topic as familiar as the sun in the desert. The authors conducted a double-blind study in an emergency department, comparing the effects of tramadol and hydrocodone-acetaminophen on acute musculoskeletal pain. It's like a scientific quest for the best painkiller in the desert of pain relief.

Hydrocodone-Acetaminophen: The Winner Emerges

The results revealed that hydrocodone-acetaminophen outperformed tramadol in alleviating pain. This is like discovering a hidden spring in the desert, offering much-needed relief. Hydrocodone-acetaminophen provided significantly lower pain scores starting from 30 minutes after dosing, a powerful testament to its effectiveness.

Navigating Pain Relief: A Desert Oasis

This study provides valuable insights for managing pain in the emergency setting. It's like finding a route through a sandstorm—knowing which medication works best can make a significant difference in a patient's experience.

Dr. Camel's Conclusion

When it comes to acute musculoskeletal pain, hydrocodone-acetaminophen appears to be a more effective painkiller than tramadol. This finding, like an oasis in the desert, offers valuable information for emergency department physicians seeking to provide optimal pain relief for their patients.
Date :
  1. Date Completed 1998-08-27
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

9701294

DOI: Digital Object Identifier

10.1016/s0196-0644(98)70127-1

Related Literature

Article Analysis
・Side Effects of hydrocodone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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