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A randomized trial of the effect of ritonavir in maintaining quality of life in advanced HIV disease. Advanced HIV Disease Ritonavir Study Group.

Author: CohenC, JiangP, NabulsiA, RevickiD A, SaroccoP W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This randomized placebo-controlled clinical trial found that ritonavir therapy, combined with other antiretroviral treatments, significantly contributes to maintenance of functioning and well-being over at least 6 months in patients with advanced HIV disease.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The aim of treatment for HIV disease is prolonging survival and improvement in health-related quality of life. Ritonavir is a potent, orally bioavailable HIV protease inhibitor with demonstrated impact on surrogate endpoints, AIDS-defining disease, and mortality. OBJECTIVES: To evaluate...See full text at original site
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引用元：
https://doi.org/10.1097/00002030-199812000-00012

データ提供：米国国立医学図書館（NLM）

Improving Quality of Life in Advanced HIV Disease

Advanced HIV disease can significantly impact a person's quality of life, both physically and emotionally. This research evaluates the effects of ritonavir, a potent HIV protease inhibitor, on patient functioning and well-being. The authors, like compassionate desert guides, have conducted a randomized, placebo-controlled clinical trial to assess the impact of ritonavir on quality of life in patients with advanced HIV disease. Their findings demonstrate that ritonavir therapy, combined with other antiretroviral treatments, can significantly contribute to maintaining functioning and well-being in these patients, offering a beacon of hope for those living with advanced HIV disease.

A Path to Improved Well-being in Advanced HIV Disease

This research underscores the importance of addressing not only the physical aspects of HIV disease but also the psychological and social well-being of patients. The study's findings suggest that ritonavir therapy can significantly improve quality of life in patients with advanced HIV disease, promoting both physical functioning and mental health. This research emphasizes the need for a holistic approach to HIV care, considering the multifaceted impact of the disease on individuals' lives.

Finding an Oasis of Hope in the Desert of HIV Disease

This research offers a ray of hope for those living with advanced HIV disease, demonstrating that ritonavir therapy can significantly improve quality of life. The study's findings highlight the importance of continued research and development of new treatments that not only address the physical aspects of HIV but also improve the overall well-being of patients. Remember, just like a camel finding a refreshing oasis in the vast desert of HIV disease, finding effective treatments can provide a sense of hope and improve the quality of life for individuals living with this challenging condition.

Dr.Camel's Conclusion

This study is like a camel caravan traversing the challenging desert of advanced HIV disease, seeking to find a path to improved quality of life for those living with this condition. By understanding the impact of ritonavir therapy, we can offer patients a more fulfilling and meaningful journey through this difficult terrain.

Date :
  1. Date Completed 1998-11-24
  2. Date Revised 2019-07-18
Further Info :

Pubmed ID

9727571

DOI: Digital Object Identifier

10.1097/00002030-199812000-00012

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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