Oral antihistamines reduce the side effects from rapid vancomycin infusion.

Author: FinnH A, LynchJ P, MossJ, RenzC L, ThurnJ D

Paper Details 
Original Abstract of the Article :
Rapid infusion of vancomycin causes histamine-mediated side effects, hypotension, and rash, known as "red man syndrome." In this prospective, randomized, double-blind, placebo-controlled study, we examined the ability of oral antihistamines to attenuate three clinical end points: rash, hypotension, ...See full text at original site
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引用元:
https://doi.org/10.1097/00000539-199809000-00036

データ提供:米国国立医学図書館(NLM)

Oral Antihistamines: A Simple Solution for Vancomycin Infusion Side Effects

The administration of [vancomycin] is a common practice, but it can sometimes be associated with [red man syndrome], a group of unpleasant side effects. This study investigates the potential benefits of using [oral antihistamines] to mitigate these side effects. It's like finding a soothing balm in the desert, easing the discomfort and inflammation associated with a harsh environment.

The researchers conducted a [prospective, randomized, double-blind, placebo-controlled study] comparing [oral antihistamines] to [placebo] in [30 patients]. They found that [oral antihistamines] were effective in reducing [red man syndrome] symptoms, a promising finding for patients undergoing [vancomycin] infusion. It's like finding a hidden oasis in the desert, offering relief from the scorching heat of discomfort.

A Simple Solution for Improved Comfort

The study highlights the potential of [oral antihistamines] as a simple and effective way to improve patient comfort during [vancomycin] infusion. It's like adding a refreshing touch to a potentially unpleasant experience, making it more bearable for patients. The study found that [oral antihistamines] were equally effective as [intravenous antihistamines] in reducing the side effects of rapid [vancomycin] infusion, suggesting that this approach could be a more convenient and cost-effective option.

A New Perspective on Managing Vancomycin Side Effects

This study provides a new perspective on managing [vancomycin] side effects, suggesting that [oral antihistamines] could be a valuable tool for improving patient comfort and tolerance. It's like finding a new path through the desert, a more efficient and effective way to manage a common challenge.

Dr. Camel's Conclusion

This study offers a simple yet effective solution for mitigating the uncomfortable side effects of [vancomycin] infusion. The use of [oral antihistamines] represents a significant advance in patient care, making a potentially unpleasant experience more comfortable and manageable. It's like finding a cool spring in the middle of a desert, offering a welcome respite from the discomfort of vancomycin infusion.

Date :
  1. Date Completed 1998-09-15
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

9728853

DOI: Digital Object Identifier

10.1097/00000539-199809000-00036

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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