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Effects of long-term testosterone, gonadotropin-releasing hormone agonist, and pimozide treatments on gonadotropin II levels and ovarian development in juvenile female striped bass (Morone saxatilis).

Author: HassinS, HollandM C, ZoharY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

This study investigated the juvenile female reproductive axis's response to hormonal stimulation in striped bass. Results indicate that while the pituitary is responsive to stimulation by testosterone and GnRH agonist, resulting in elevated GtH II levels, this did not lead to precocious puberty, suggesting other factors are necessary for ovarian development.
Paper Details　
Original Abstract of the Article :
The ability of the juvenile female reproductive axis to respond to hormonal stimulation was investigated in a Perciform fish, the striped bass (Morone saxatilis) using various combinations of testosterone (T), GnRH agonist (GnRHa), and pimozide. A long-term treatment with T alone, or T in combinatio...See full text at original site
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引用元：
https://doi.org/10.1095/biolreprod59.5.1153

データ提供：米国国立医学図書館（NLM）

Hormonal Regulation of Gonadotropin Levels in Striped Bass

This research investigates the effects of long-term treatment with testosterone (T), gonadotropin-releasing hormone agonist (GnRHa), and pimozide on gonadotropin II levels and ovarian development in juvenile female striped bass. The authors, like skilled marine biologists studying the delicate balance of a coastal ecosystem, explore the complex interplay of hormones in regulating the reproductive cycle of striped bass.

Hormonal Effects on Gonadotropin Levels

This research provides valuable insights into the hormonal regulation of gonadotropin levels in striped bass. The authors found that both T and GnRHa stimulate the accumulation of gonadotropin II in the pituitary gland, but only high doses of GnRHa in combination with T were able to induce its release. The study also found that pimozide, a dopamine antagonist, inhibits the release of gonadotropin II.

Understanding Reproductive Physiology in Fish

This research contributes to our understanding of the complex endocrine mechanisms that regulate reproduction in fish. The findings suggest that the juvenile striped bass pituitary is responsive to hormonal stimulation, but further factors are required to initiate ovarian development.

Dr. Camel's Conclusion

This research explores the complex hormonal regulation of gonadotropin levels and ovarian development in striped bass. The findings provide valuable insights into the reproductive physiology of this important fish species, contributing to our understanding of the delicate balance of hormones and their impact on reproductive processes.
Date :
  1. Date Completed 1998-12-22
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

9780322

DOI: Digital Object Identifier

10.1095/biolreprod59.5.1153

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Languages

English

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