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Effect of therapy with deflazacort on dyslipoproteinemia after pediatric renal transplantation.
Author: BrandiP, FerrarisJ R, LegalS, OyhamburuJ, PasqualiniT, SorrocheP
Original Abstract of the Article :
Deflazacort is an oxazolone compound derived from prednisolone, with similar immunosuppressive action but fewer side effects. Kidney function, weight/height ratio, serum triglycerides, cholesterol, high-density lipoprotein (HDL) cholesterol, very-low-density lipoprotein cholesterol, low-density lipo...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/s0022-3476(98)70063-0
データ提供:米国国立医学図書館(NLM)
Deflazacort's Impact on Dyslipoproteinemia After Pediatric Renal Transplantation
This study explores the effects of deflazacort, a steroid medication, on dyslipoproteinemia, a condition affecting lipid levels in the blood, in children who have undergone renal transplantation. The research compares the effects of deflazacort with those of methylprednisone, a traditional steroid treatment. The study found that substituting deflazacort for methylprednisone resulted in significant improvements in the lipoprotein profile of these children. Deflazacort led to a reduction in total cholesterol, LDL cholesterol, and the TC/HDL cholesterol ratio, while increasing HDL cholesterol and apolipoprotein A. This study highlights the potential of deflazacort as a more effective and potentially less harmful treatment option for managing dyslipoproteinemia after pediatric renal transplantation.A Better Approach to Post-Transplantation Care
This study provides valuable insights into the management of dyslipoproteinemia in children after renal transplantation. The research highlights the potential benefits of deflazacort, demonstrating its effectiveness in improving lipid profiles and potentially minimizing the risks associated with traditional steroid treatment. Imagine this research as a desert oasis, providing a more sustainable and effective solution for managing the complex challenges of post-transplantation care.Improved Health Outcomes for Children After Transplantation
This study suggests that deflazacort could contribute to better health outcomes for children who have undergone renal transplantation. By improving lipid profiles and potentially minimizing side effects, deflazacort could enhance the long-term health and well-being of these children. It's like a desert spring, providing a vital source of nourishment and support for their continued health and development.Dr.Camel's Conclusion
This study delves into the effects of deflazacort on dyslipoproteinemia in children after renal transplantation. The research highlights the potential benefits of deflazacort, suggesting that it could be a more effective and potentially less harmful treatment option compared to traditional steroid therapy. As a research camel, I'm always seeking new solutions for improving the health and well-being of children, and this study offers a promising path forward in the management of post-transplantation care.Date :
- Date Completed 1998-11-25
- Date Revised 2019-06-30
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