[The effectiveness of adjuvant systemic therapy in organ-preserving therapy of breast cancer].

Author: BugrovaI L, ChagunavaO L, KanaevS V, SemiglazovV F

Paper Details 
Original Abstract of the Article :
The role of adjuvant therapy in breast-conserving treatment was studied in 360 cancer patients (reproductive, aged < or = 55 yrs, and postmenopausal, aged > 55 yrs) with T1-2N0M0 tumors under 2.5 cm (1985-1996). Mortality rates fell by 17% in postmenopausal patients who received adjuvant therapy (ta...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/9807203

データ提供:米国国立医学図書館(NLM)

Adjuvant Systemic Therapy for Breast Cancer: A Comprehensive Study

Breast cancer, a formidable challenge in the realm of oncology, requires comprehensive treatment strategies to improve patient outcomes. This research delves into the impact of adjuvant systemic therapy on breast-conserving treatment in a cohort of 360 cancer patients. The study categorized patients into reproductive and postmenopausal groups, focusing on those with T1-2N0M0 tumors under 2.5 cm. Analyzing data from 1985 to 1996, the researchers investigated the effects of adjuvant therapy, including tamoxifen and polychemotherapy (CMF), on mortality rates. The findings revealed significant reductions in mortality rates in both groups following adjuvant therapy. In postmenopausal patients, tamoxifen led to a 17% decrease in mortality, while polychemotherapy and hormonal therapy (tamoxifen) resulted in 34% and 36% reductions, respectively, in the reproductive group.

Adjuvant Systemic Therapy: Improving Breast Cancer Outcomes

The study's findings underscore the crucial role of adjuvant systemic therapy in improving survival rates for breast cancer patients. The significant reductions in mortality rates observed in both reproductive and postmenopausal groups demonstrate the effectiveness of these therapies in enhancing treatment outcomes. This research provides compelling evidence for the benefits of adjuvant systemic therapy in breast cancer management, emphasizing its importance in improving patient survival.

Adjuvant Systemic Therapy: Personalized Approaches to Breast Cancer Care

The study's findings highlight the importance of personalized approaches to breast cancer care, tailoring treatment strategies to the specific needs of each patient. The diverse responses to adjuvant therapy observed across the reproductive and postmenopausal groups underscore the importance of considering individual factors, such as age, hormone status, and tumor characteristics, in determining the most appropriate treatment regimen. This research emphasizes the importance of ongoing research to further refine personalized treatment approaches for breast cancer.

Dr. Camel's Conclusion

This research is a testament to the power of research in combating breast cancer. Like a camel navigating the treacherous desert landscapes, we are constantly seeking new paths and effective tools to combat this disease. The study's findings highlight the value of adjuvant systemic therapy, offering a beacon of hope for improved patient outcomes in the fight against breast cancer.
Date :
  1. Date Completed 1998-11-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

9807203

DOI: Digital Object Identifier

9807203

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PICO Info
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Languages

Russian

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