Paper Details

  1. Home
  2. Paper Details

Comparison of the efficacy and side-effects of ondansetron and metoclopramide-diphenhydramine administered to control nausea and vomiting in children treated with antineoplastic chemotherapy: a prospective randomized study.

Author: AtayA A, KöseogluV, KürekçiA E, OzcanO, SariciU, SoriciU

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ondansetron was more effective than metoclopramide-diphenhydramine in preventing nausea and vomiting in children treated with antineoplastic chemotherapy.
Paper Details　
Original Abstract of the Article :
Nausea and vomiting following antineoplastic therapy in patients receiving chemotherapy remains a problem. To prevent nausea and vomiting due to antineoplastic therapy, many types of drugs have been used. Ondansetron and the combination metoclopramide-diphenhydramine have been widely used in childre...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s004310050940

データ提供：米国国立医学図書館（NLM）

Ondansetron vs. Metoclopramide-Diphenhydramine: Navigating the Sands of Chemotherapy-Induced Nausea

Chemotherapy, a vital treatment for cancer, can often cause debilitating nausea and vomiting. This study investigates the effectiveness of two anti-emetic medications, ondansetron and metoclopramide-diphenhydramine, in controlling nausea and vomiting in children undergoing antineoplastic chemotherapy.

Ondansetron: A More Effective Antiemetic

The researchers conducted a prospective randomized study comparing the efficacy and side effects of these medications in children receiving chemotherapy. They found that ondansetron was more effective in preventing chemotherapy-induced nausea and vomiting, particularly in patients receiving cisplatin. This finding is like discovering a hidden oasis in the vast desert, offering respite from the harsh side effects of chemotherapy. Metoclopramide-diphenhydramine, on the other hand, was associated with more side effects.

Improving the Quality of Life for Children with Cancer

This research provides valuable insights into the management of chemotherapy-induced nausea and vomiting in children. It suggests that ondansetron may be a more effective option for controlling this distressing side effect, improving the quality of life for children undergoing cancer treatment. It's a reminder that even in the face of challenging medical conditions, we can find ways to alleviate suffering and improve patient well-being. It underscores the importance of careful medication selection to minimize side effects and optimize treatment outcomes.

Dr. Camel's Conclusion

This study provides valuable insights into the treatment of chemotherapy-induced nausea and vomiting in children. It highlights the importance of selecting the most effective antiemetic medication to improve patient comfort and well-being. Just as a careful traveler chooses the right supplies for a desert journey, so too must healthcare professionals choose the most appropriate medications to optimize treatment outcomes.
Date :
  1. Date Completed 1998-12-30
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

9809818

DOI: Digital Object Identifier

10.1007/s004310050940

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.