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[The effects of midazolam on oxygen consumption and the level of vigilance. The possibility of the sedative effect of the plexiglas dome (canopy) of the Deltatrac indirect calorimetry device].
Author: AuquierP, BruderN, DumontJ C, FrançoisG, KerbaulF
Original Abstract of the Article :
OBJECTIVE: To assess the effects of midazolam on oxygen consumption (VO2) and the level of vigilance. To search for a possible "sedative effect" of the canopy of the Deltatrac (Datex) when a placebo is administered instead of midazolam. STUDY DESIGN: Prospective, comparative, randomized, double-bli...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/s0750-7658(00)80004-0
データ提供:米国国立医学図書館(NLM)
Measuring Oxygen Consumption: A Tale of Two Sedatives
Oxygen consumption is a vital indicator of our health, like a camel’s ability to navigate a sandstorm. This study explored the effects of midazolam, a sedative, on oxygen consumption and the level of vigilance, which is like measuring the camel's ability to stay alert and aware of its surroundings.
The study found that midazolam significantly decreased oxygen consumption in healthy volunteers, but there was no significant difference in oxygen consumption between the midazolam group and the placebo group. This is like a camel taking a rest under a shady tree, reducing its energy expenditure but not losing its ability to navigate the desert.
The Mystery of the Canopy
The study also investigated the potential sedative effect of a plexiglass dome used in the oxygen consumption measurement device. This is like trying to understand if the shade of a tree can induce drowsiness in a camel.
Staying Alert in the Desert
This research reminds us that understanding the effects of medication on both our physical and cognitive function is critical, especially when it comes to sedatives. It’s important to be aware of potential side effects and consult with a medical professional if you have any concerns. Like a camel navigating a sandstorm, we need to stay alert and aware of our surroundings.
Dr.Camel's Conclusion
This study highlights the intricacies of oxygen consumption and its relationship with sedation. It’s a reminder that even seemingly simple measurements can reveal complex and nuanced effects of medication on our bodies.
Date :
- Date Completed 1998-12-18
- Date Revised 2019-08-31
Further Info :
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