Paper Details

  1. Home
  2. Paper Details

A prospective study of bone loss and turnover after allogeneic bone marrow transplantation: effect of calcium supplementation with or without calcitonin.

Author: KetoP, KinnunenK, LaitinenK, LöyttyniemiE, MäkeläP, RuutuT, TähteläR, VolinL, VälimäkiM J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated bone loss after allogeneic bone marrow transplantation (BMT) and the potential benefits of calcium and calcitonin in preventing bone loss. The study found that significant bone loss occurs after BMT and that calcium with or without calcitonin does not prevent it.
Paper Details　
Original Abstract of the Article :
Transplantation of solid organs including heart, kidney, and liver is associated with rapid bone loss and increased rate of fracture; data on bone marrow transplantation recipients (BMT) are scarce. The purpose of the present study was to examine the magnitude, timing, and mechanism of bone loss fol...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1038/sj.bmt.1701586

データ提供：米国国立医学図書館（NLM）

A Prospective Study of Bone Loss and Turnover After Allogeneic Bone Marrow Transplantation: Effect of Calcium Supplementation with or Without Calcitonin

This study investigates the challenging terrain of bone loss following allogeneic bone marrow transplantation (BMT), where the body’s own bone marrow is replaced with donor marrow. The authors are like researchers exploring a vast desert, searching for solutions to prevent bone loss in these patients. They conducted a prospective study to assess the effectiveness of calcium supplementation with or without calcitonin in preventing bone loss after BMT. The results show that despite the use of calcium and calcitonin, the bone loss remained significant, highlighting the complexity of this condition.

Navigating the Shifting Sands: Bone Loss After Bone Marrow Transplantation

This study reveals the significant bone loss that occurs after BMT, a challenging condition for patients undergoing this life-saving procedure. The authors found that calcium supplementation with or without calcitonin was not effective in preventing bone loss, highlighting the need for further research into more effective strategies for preserving bone health in these individuals.

A Fragile Foundation: Protecting Bone Health After Bone Marrow Transplantation

This study emphasizes the need to find more effective ways to prevent bone loss after BMT. The authors found that calcium and calcitonin were not sufficient to protect bone health, highlighting the complexity of this condition and the need for further research to develop more effective treatments.

Dr.Camel's Conclusion

This study sheds light on the complex challenge of bone loss after BMT, a condition that requires further investigation and innovative approaches. It's like navigating a desert with shifting sands, reminding us that bone health is a delicate balance that needs careful attention, especially in patients who have undergone this life-changing procedure.

Date :
  1. Date Completed 1999-06-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10100579

DOI: Digital Object Identifier

10.1038/sj.bmt.1701586

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.