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Nebivolol versus enalapril in essential hypertension: a long-term double-blind comparative trial.
Author: DupontA G, Rishøj NielsenM, RobertsonJ I, Van NuetenL, VertommenC
Original Abstract of the Article :
Nebivolol was compared in a dose of 5 mg once daily with enalapril 10 mg once daily over 7 months in a double-blind randomised trial in essential hypertension. The two drugs had very similar sustained effects in lowering both systolic and diastolic pressures; neither had an orthostatic component. Bo...See full text at original site
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引用元:
https://doi.org/10.1080/17843286.1999.11754204
データ提供:米国国立医学図書館(NLM)
Nebivolol and Enalapril: A Head-to-Head Showdown in Essential Hypertension
In the vast landscape of hypertension research, finding effective and safe medications is a constant quest. This study delved into the world of essential hypertension, a condition where blood pressure consistently remains elevated. The researchers used a double-blind randomized trial, a technique like a game of hide-and-seek where neither the participants nor the researchers know who's getting which treatment, to compare the effects of Nebivolol and Enalapril, two medications commonly used to lower blood pressure. This study aimed to evaluate the efficacy and safety of these two medications in reducing both systolic and diastolic blood pressure over a 7-month period. Interestingly, they found that both drugs effectively lowered blood pressure in a sustained manner, with no significant orthostatic effects, meaning that the blood pressure didn't drop dramatically when participants stood up. Both drugs were well-tolerated, with no concerning side effects detected in terms of blood count, liver function, or kidney function.The Takeaway: Nebivolol and Enalapril Are Both Effective, But Which One Is Better?
Both medications showed similar efficacy in lowering blood pressure, making them viable options for managing essential hypertension. However, the authors didn't delve into other factors like long-term effects or specific patient characteristics that could influence the choice between these two drugs. Therefore, further research is needed to guide clinicians in choosing the most appropriate medication for individual patients.The Impact on Your Health: Navigating Hypertension Treatment
It's important to remember that high blood pressure is a serious condition that requires careful management. Consult with your doctor to determine the most appropriate treatment for your specific situation, as they can consider factors like your medical history, lifestyle, and other medications you may be taking. Remember, effective treatment of hypertension can help prevent complications like heart disease, stroke, and kidney failure.Dr. Camel's Conclusion
This study provides valuable insights into the efficacy and safety of Nebivolol and Enalapril in essential hypertension. While both drugs prove effective, further research is needed to understand their long-term effects and tailor treatments to individual patients. Remember, hypertension is a silent killer, so don't underestimate the importance of regular blood pressure checks and appropriate medical management.Date :
- Date Completed 1999-05-04
- Date Revised 2019-09-09
Further Info :
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PICO Info
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Languages
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