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Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgery.
Author: AlfieriO, CaloriG, CasatiV, CossoliniM, GuzzonD, OppizziM, TorriG
Original Abstract of the Article :
BACKGROUND: The effects of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) on bleeding and allogeneic transfusions, and the cost of pharmacological and transfusional treatment were compared to aprotinin (AP). METHODS: We randomized 210 patients subjected to elective cardiac surgery. Of th...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/s0003-4975(99)00866-8
データ提供:米国国立医学図書館(NLM)
Hemostatic Effects in Cardiac Surgery
This research explores the use of various hemostatic agents in cardiac surgery, a field where minimizing bleeding is crucial for patient safety. It's like navigating a desert landscape, where every drop of blood is precious and requires careful management. This research delves into the effectiveness of different hemostatic agents, comparing their impact on bleeding, transfusion needs, and overall cost effectiveness.Comparing Hemostatic Agents
The study compares the efficacy of aprotinin, tranexamic acid (TA), and epsilon-aminocaproic acid (EACA) in minimizing blood loss and transfusion requirements. It's like comparing different water sources in the desert, evaluating their efficiency and effectiveness. This study provides valuable insights into the pros and cons of each agent, helping clinicians choose the best option for individual patients.Balancing Efficacy and Cost
The research highlights the importance of considering not only the effectiveness of hemostatic agents but also their cost-effectiveness. It's like finding a sustainable water source in the desert, ensuring that the benefits outweigh the resources required. This study suggests that TA may offer a cost-effective alternative to aprotinin while achieving similar outcomes in reducing bleeding and transfusion needs.Dr.Camel's Conclusion
This research is like finding a hidden oasis of knowledge in the desert of cardiac surgery. It provides valuable insights into the effectiveness and cost-effectiveness of different hemostatic agents, guiding clinicians toward the most appropriate treatment choices for their patients. It's a reminder that in the demanding world of surgery, even the smallest details can have a significant impact on patient outcomes.Date :
- Date Completed 2000-01-13
- Date Revised 2019-06-28
Further Info :
Related Literature
SNS
PICO Info
in preparation
Languages
English
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