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Clomiphene citrate for unexplained subfertility in women.

Author: CollinsJ, HughesE, VandekerckhoveP

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Clomiphene citrate is effective in treating sub-fertility associated with oligo-ovulation. However, it is associated with an elevated multiple pregnancy rate of approximately 10%. Other side effects include hot flashes, mood swings, headaches, and visual disturbances. The potential for increased ovarian cancer risk is a concern.
Paper Details　
Original Abstract of the Article :
The effectiveness of clomiphene citrate has been clearly demonstrated in the treatment of sub-fertility associated with oligo-ovulation. The multiple pregnancy rate associated with clomiphene, however, is elevated at approximately 10%. Additional side effects associated with clomiphene use also incl...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD000057

データ提供：米国国立医学図書館（NLM）

Clomiphene Citrate for Unexplained Subfertility: A Critical Look

My fellow researchers, we're delving into the realm of [reproductive medicine] and examining the effectiveness of clomiphene citrate in treating unexplained subfertility. This study, like a camel traversing a vast desert, seeks to illuminate the benefits and risks associated with this medication. The researchers explored the use of clomiphene citrate in women with unexplained subfertility, considering its effectiveness, potential side effects, and the controversy surrounding its potential link to increased ovarian cancer risks. This comprehensive approach is similar to the way a desert traveler carefully assesses the risks and benefits of each route they take, ensuring a safe and successful journey.

Assessing the Effectiveness of Clomiphene Citrate

The study confirmed the effectiveness of clomiphene citrate in treating subfertility associated with oligo-ovulation. However, it also highlighted the elevated multiple pregnancy rate associated with this medication, approximately 10%. This is like a desert oasis that provides a respite from the harsh environment but may also attract a large number of travelers, increasing the chances of conflict.

Weighing the Risks and Benefits

The study also highlighted other potential side effects of clomiphene citrate, including hot flashes, mood swings, headaches, and visual disturbances. The potential link to increased ovarian cancer risks further complicates the decision-making process. This is like a desert traveler who encounters a beautiful oasis, but must carefully consider the risks of potential predators or dangerous wildlife before fully indulging in its benefits.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness and potential risks associated with clomiphene citrate for unexplained subfertility. It highlights the need for careful consideration of the individual patient's circumstances, including their risk tolerance and desired outcome. This research underscores the importance of informed decision-making in healthcare, a process that requires careful navigation, just like a camel navigating the challenging terrain of the desert.

Date :
  1. Date Completed 2001-07-05
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

10908459

DOI: Digital Object Identifier

10.1002/14651858.CD000057

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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