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A double-blind, placebo-controlled study of the effects of lithium on cognition in healthy subjects: mild and selective effects on learning.

Author: DufresneJ, LussierI, StipE, YathamL

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the effects of lithium on cognitive function in healthy subjects. Lithium did not produce significant cognitive impairment in the study participants.
Paper Details　
Original Abstract of the Article :
Several studies have shown cognitive impairment in short-term memory, long-term memory and psychomotor speed in bipolar patients taking lithium. The aim of the study was to look at the effect of lithium in normal subjects (N=30) taking lithium for 3 weeks. A comprehensive battery was used to assess ...See full text at original site
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引用元：
https://doi.org/10.1016/s0165-0327(99)00178-0

データ提供：米国国立医学図書館（NLM）

Lithium: A Potential Cognitive Enhancer or a Desert Mirage?

The [pharmacology] of [lithium] has long been a subject of interest, particularly its effects on [cognition]. This research investigates the cognitive effects of lithium in a double-blind, placebo-controlled study involving healthy subjects. The study aimed to evaluate the impact of lithium on various cognitive domains, including [attention] and [memory].

The Cognitive Effects of Lithium: A Complex Landscape

The study's findings revealed that lithium had a mild and selective effect on [learning], suggesting that it may have some potential as a cognitive enhancer. However, the results also highlight the need for further research to fully understand the complex effects of lithium on cognition. The desert of pharmacology is filled with complexities, and understanding the nuances of lithium's effects on cognition is a journey that requires careful exploration.

Implications for Lithium Use: A Desert Oasis or a Mirage?

This study offers a glimpse into the potential of lithium to enhance certain cognitive abilities, but it also reminds us that the desert of pharmacology is vast and complex. Further research is needed to fully understand the nuances of lithium's effects on cognition and to determine its potential benefits and risks. It is important to consult with a healthcare professional before using lithium to ensure it is safe and appropriate for your specific needs.

Dr.Camel's Conclusion

This research provides valuable insights into the cognitive effects of lithium, suggesting that it may hold some potential as a cognitive enhancer. However, the desert of pharmacology is vast and complex, and further exploration is needed to fully understand the intricacies of lithium's effects on cognition. Remember, the desert is full of mirages, so it's crucial to approach any new treatment with caution and seek guidance from a qualified healthcare professional.

Date :
  1. Date Completed 2001-02-02
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

11074103

DOI: Digital Object Identifier

10.1016/s0165-0327(99)00178-0

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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