Paper Details

  1. Home
  2. Paper Details

[Does the addition of an anxiolytic drug improve the anti-emetic effectiveness of the steroid and granisetron combination in the prophylaxis of cisplatin-induced vomiting?].

Author: BagamériA, KulcsárT, LehoczkyO, PulayT, SárosiZ

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study compared two forms of antiemetic therapy for gynecological cancer patients treated with cisplatin chemotherapy. The addition of an anxiolytic drug did not improve the antiemetic effectivity of the granisetron-methylprednisolone combination in the first 24 hours of cisplatin chemotherapy.
Paper Details　
Original Abstract of the Article :
Authors evaluated two forms of antiemetic therapy in 129 courses of 51 gynecological cancer patients treated with cisplatin chemotherapy of moderately or highly emetic dose (50-100 mg/m2) in a prospective, non randomized study. The patients received granisetron (3 mg, intravenously) and methylpredni...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/11556262

データ提供：米国国立医学図書館（NLM）

Antiemetic Strategies for Cisplatin-Induced Vomiting

This research investigates the effectiveness of different antiemetic combinations in preventing cisplatin-induced vomiting in gynecological cancer patients. The authors compared the efficacy of granisetron and methylprednisolone with and without the addition of an anxiolytic drug. They found that the addition of an anxiolytic drug did not significantly improve the antiemetic effectiveness of the combination therapy.

Navigating the Side Effects of Chemotherapy

The authors explore the challenges of managing the side effects of chemotherapy, particularly the debilitating effects of cisplatin-induced vomiting. This can be likened to a traveler navigating a harsh desert, encountering unexpected challenges and seeking ways to mitigate their impact. The authors' research investigates different antiemetic strategies to provide relief for patients undergoing chemotherapy.

Finding the Right Combination

The authors' research highlights the importance of finding the right combination of antiemetic drugs to effectively prevent cisplatin-induced vomiting. This is like a camel adapting its journey to the specific challenges of the desert, choosing the most appropriate path and utilizing its unique capabilities to overcome obstacles. Similarly, healthcare professionals need to carefully select the most effective antiemetic strategies to provide optimal care for patients.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness of different antiemetic combinations for preventing cisplatin-induced vomiting. The authors' findings highlight the importance of selecting the most appropriate strategies for individual patients to minimize the side effects of chemotherapy. Just as a camel navigates a challenging desert environment, healthcare professionals need to be equipped with the knowledge and tools to effectively manage the side effects of cancer treatment, providing patients with the best possible care and support.
Date :
  1. Date Completed 2002-03-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11556262

DOI: Digital Object Identifier

11556262

SNS
PICO Info
in preparation
Languages

Hungarian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.