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The anti-allergic effects of a cromolyn sodium-chlorpheniramine combination compared to ketotifen in the conjunctival allergen challenge model.

Author: BuscaF, LeonardiA, SecchiA G, TavolatoM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Evaluation StudyResearch that systematically evaluates the effectiveness of a particular program or policy. It measures its outcomes and provides important information for future decision-making.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cromolyn sodium (DSCG) 4% with the antihistamine, chlorpheniramine, is more effective than ketotifen 0.05% at preventing itching and redness in the conjunctival allergen challenge (CAC) model.
Paper Details　
Original Abstract of the Article :
PURPOSE: To compare the inhibitory effects of a topical combination product, cromolyn sodium (DSCG) 4% with the antihistamine, chlorpheniramine, with those of topical ketotifen 0.05% on the clinical allergic reaction induced by the conjunctival allergen challenge (CAC). METHODS: Ten allergic but no...See full text at original site
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引用元：
https://doi.org/10.1177/112067210301300202

データ提供：米国国立医学図書館（NLM）

Conjunctival Allergen Challenge: A Camel's Journey Through the Desert of Allergies

Allergic conjunctivitis, a common condition affecting the eyes, can be likened to a desert sandstorm, causing irritation, redness, and itching. This study investigates the effectiveness of two topical medications, cromolyn sodium (DSCG) 4% with chlorpheniramine and ketotifen 0.05%, in preventing allergic reactions in the eyes. The researchers conducted a conjunctival allergen challenge, exposing patients to specific allergens and observing their reaction to the medications.

Navigating the Desert of Allergies: A Camel's Perspective on Treatment

The study found that DSCG-chlorpheniramine was more effective than ketotifen in preventing itching and redness in response to the allergen challenge. This finding suggests a potential advantage for this combination medication in managing allergic conjunctivitis. It's like finding a protective oasis in the desert, providing a shield against the irritating effects of allergens.

Allergic Conjunctivitis: A Camel's Advice for Protecting Your Eyes

Allergic conjunctivitis can be uncomfortable and disruptive, but there are options available to manage symptoms. It's like navigating a desert, requiring attention to protecting yourself from the elements. Discuss treatment options with your ophthalmologist, consider using medications like DSCG-chlorpheniramine, and take steps to avoid known allergens. Remember, with proper care and attention, you can protect your eyes and minimize the impact of allergic conjunctivitis.

Dr.Camel's Conclusion

This study highlights the potential benefits of DSCG-chlorpheniramine in managing allergic conjunctivitis, offering a promising option for patients seeking relief from itchy and irritated eyes. It's a reminder that even in the challenging desert of allergies, there are oases of innovation and research, guiding us towards more effective treatments and improved quality of life.

Date :
  1. Date Completed 2003-05-12
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

12696630

DOI: Digital Object Identifier

10.1177/112067210301300202

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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