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Unintended events following immunization with MMR: a systematic review.

Author: , BiancoElvira, DemicheliVittorio, JeffersonTom, PriceDeirdre

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A systematic review of 22 studies found that the MMR vaccine is associated with a lower incidence of upper respiratory tract infections, a higher incidence of irritability, and similar incidence of other adverse effects compared to placebo. It is likely associated with benign thrombocytopenic purpura (TP), parotitis, joint and limb complaints, and aseptic meningitis (mumps Urabe strain-containing MMR). Exposure to MMR is unlikely to be associated with Crohn's disease, ulcerative colitis, autism, or aseptic meningitis (mumps Jeryl-Lynn strain-containing MMR).
Paper Details　
Original Abstract of the Article :
Public debate over the safety of the trivalent measles, mumps and rubella (MMR) vaccine and the drop in vaccination rates in several countries persists despite its almost universal use and accepted effectiveness. We carried out a systematic review to assess the evidence of unintended effects (benefi...See full text at original site
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引用元：
https://doi.org/10.1016/s0264-410x(03)00271-8

データ提供：米国国立医学図書館（NLM）

MMR Vaccine: A Look at Safety and Effectiveness

The MMR vaccine, which protects against measles, mumps, and rubella, is a cornerstone of public health. However, concerns about its safety have persisted, leading to a decline in vaccination rates in some areas. This study aimed to systematically review the evidence regarding the unintended effects of the MMR vaccine. The researchers conducted a comprehensive search of medical literature, focusing on studies comparing the MMR vaccine to placebo in healthy individuals up to 15 years of age.

MMR Vaccine: A Beacon of Protection

The review found that the MMR vaccine is associated with a lower incidence of upper respiratory tract infections and a similar incidence of other adverse effects compared to placebo. While the MMR vaccine is likely associated with some minor side effects, such as irritability, it also appears to protect against more serious complications. The study emphasizes the importance of vaccination for preventing measles, mumps, and rubella, which can have significant health consequences.

Navigating the Desert of Vaccine Misinformation

The study provides valuable evidence to dispel misinformation about the MMR vaccine. It highlights the overwhelming benefits of vaccination in protecting individuals and communities from potentially devastating diseases. Like a camel navigating a desert landscape, we must be vigilant in seeking credible information and avoiding the pitfalls of misinformation. Vaccination is a key tool for preventing disease and ensuring a healthier future for all.

Dr.Camel's Conclusion

The study provides a comprehensive overview of the safety and effectiveness of the MMR vaccine, reinforcing its vital role in public health. The evidence clearly shows that the benefits of vaccination far outweigh the risks. It's crucial to rely on credible scientific evidence and to work together to combat misinformation, ensuring that everyone has access to the protection provided by vaccines.

Date :
  1. Date Completed 2004-03-25
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

12922131

DOI: Digital Object Identifier

10.1016/s0264-410x(03)00271-8

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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