Efficacy and tolerability profile of nebivolol vs atenolol in mild-to-moderate essential hypertension: results of a double-blind randomized multicentre trial.

Author: ChanuBernard, FacchiniAnnalisa, GrassiGuido, ManciaGiuseppe, ToutouzasTorakis, TrevanoFosca Quarti

Paper Details 
Original Abstract of the Article :
The objective of this 12-week double-blind randomized multicentre study was to compare the efficacy and tolerability of nebivolol, a recently developed beta-blocking agent with vasodilating properties, to the classical beta-blocker atenolol. After a placebo run-in phase, 205 mild-to-moderate middle-...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14761075

データ提供:米国国立医学図書館(NLM)

Nebivolol vs. Atenolol: A Race for the Best Treatment in Hypertension

The world of high blood pressure treatment is a vast desert, with numerous medications vying for a place in the therapeutic oasis. This study compares the effectiveness and tolerability of two beta-blockers, nebivolol and atenolol, in managing mild-to-moderate hypertension. The researchers conducted a [research methodology] study, comparing the effects of these medications in a group of middle-aged patients with hypertension. It's like a race across the desert, with each medication vying for the best performance.

The results of the study showed that both nebivolol and atenolol effectively lowered blood pressure, but nebivolol was better tolerated and associated with fewer side effects. This finding suggests that nebivolol may be a more suitable option for some patients with hypertension. The researchers noted that nebivolol also caused a less pronounced decrease in heart rate compared to atenolol, a potential benefit for patients who are sensitive to bradycardia (slow heart rate).

Nebivolol: A Potential Oasis in the Desert of Hypertension Treatment

The study provides evidence that nebivolol may offer a more tolerable and potentially safer alternative to atenolol for managing hypertension. This could be particularly beneficial for patients who experience side effects from atenolol or who have a high sensitivity to heart rate changes.

Navigating the Landscape of Hypertension Treatment

Finding the right medication for hypertension is like finding the right path through a vast desert. There are many options available, and what works best for one person may not be ideal for another. This study emphasizes the importance of considering individual patient characteristics and preferences when choosing a treatment for hypertension. It's essential to work with a healthcare professional to find the best approach for your specific needs.

Dr.Camel's Conclusion

This study provides valuable insights into the potential of nebivolol as a promising alternative for hypertension management. It's like finding a more comfortable and reliable camel to carry you across the desert of hypertension. The research suggests that nebivolol may be a better fit for some patients, offering an oasis of relief from the side effects that can accompany other treatments.

Date :
  1. Date Completed 2004-09-09
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

14761075

DOI: Digital Object Identifier

14761075

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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