Rapid treatment of "wearing off" in Parkinson's disease.

Author: SwopeDavid M

Paper Details 
Original Abstract of the Article :
Patients with advanced Parkinson's disease (PD) may develop a variety of motor complications associated with levodopa therapy. Motor fluctuations, such as early morning akinesia and "wearing-off," may respond to individualized medical management with titrated combinations of levodopa, dopamine agoni...See full text at original site
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引用元:
https://doi.org/10.1212/wnl.62.6_suppl_4.s27

データ提供:米国国立医学図書館(NLM)

Addressing 'Wearing Off' in Parkinson's Disease: A Multifaceted Approach

Parkinson's disease (PD) is a progressive neurological disorder that can significantly impact a person's life. One common challenge for people with PD is 'wearing off,' a phenomenon where the effects of levodopa, a medication used to treat PD, diminish over time, leading to a return of symptoms. This research provides a comprehensive overview of approaches for managing 'wearing off' and other motor complications associated with levodopa therapy. The researchers discuss strategies for individualized medical management, including titrated combinations of medications, liquid levodopa preparations, and other potential treatments.

Managing 'Wearing Off' in PD: A Collaborative Effort

This research highlights the multifaceted nature of managing PD and the importance of working closely with a healthcare professional to develop an individualized treatment plan. The researchers discuss strategies for addressing various motor complications, including 'wearing off,' early morning akinesia, and unpredictable 'off' periods. This comprehensive approach is essential for improving patient outcomes.

Understanding PD and Seeking Care

If you or someone you know is living with PD, it's essential to seek care from a specialized neurologist. They can provide accurate diagnosis, develop a personalized treatment plan, and offer ongoing support and guidance. This research underscores the importance of seeking expert care to manage PD effectively and improve quality of life.

Dr. Camel's Conclusion

Imagine PD as a desert oasis that gradually dries up as the days go by. Levodopa is like a refreshing spring that provides temporary relief, but its effects wear off like the oasis's water. This research explores different strategies for managing the oasis's dwindling water, like finding new sources of water (different medications) or using a special water-holding device (liquid levodopa). This research encourages us to think creatively and adapt our approaches to manage PD's challenges, ensuring a smoother journey through the desert.

Date :
  1. Date Completed 2004-04-29
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

15037669

DOI: Digital Object Identifier

10.1212/wnl.62.6_suppl_4.s27

SNS
PICO Info
in preparation
Languages

English

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