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Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment.

Author: BüllerH R, Dörffler-MellyJ, KoopmanM M W, PrinsM H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Balloon angioplasty is a common treatment for peripheral artery disease (PAD), but the treated arteries often narrow again (restenosis/reocclusion). This happens more often in longer blockages, poor blood flow in the lower leg, advanced disease, and people with heart disease risk factors. To prevent this, patients are given blood thinners.
Paper Details　
Original Abstract of the Article :
Peripheral arterial disease (PAD) is frequently treated by balloon angioplasty. Restenosis/reocclusion of the dilated segments occurs often depending on length of occlusion, lower leg outflow, stage of disease and presence of cardiovascular risk factors. To prevent reocclusion, patients are treated ...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD002071.pub2

データ提供：米国国立医学図書館（NLM）

Preventing Restenosis After Peripheral Endovascular Treatment

Peripheral arterial disease (PAD), a condition affecting blood flow in the legs and feet, often requires balloon angioplasty to restore blood flow. However, restenosis, the narrowing of the treated vessel, can occur, leading to a recurrence of symptoms. This research explores the role of antiplatelet and anticoagulant drugs in preventing restenosis/reocclusion following peripheral endovascular treatment.

Antithrombotic Agents: A Key Strategy

The researchers highlight the importance of antithrombotic agents, including antiplatelet and anticoagulant drugs, in preventing reocclusion following angioplasty. These medications work by inhibiting blood clot formation, reducing the risk of the treated vessel narrowing again.

A Tailored Approach to Preventing Restenosis

This research emphasizes the need for a tailored approach to managing restenosis after endovascular treatment. Factors like the length of the occlusion, lower leg outflow, stage of disease, and cardiovascular risk factors can influence the risk of restenosis. By carefully considering these factors and choosing appropriate antithrombotic agents, healthcare professionals can improve patient outcomes and minimize the risk of reocclusion.

Dr.Camel's Conclusion

This study underscores the importance of preventive measures in managing PAD. By understanding the risk factors for restenosis and utilizing appropriate antithrombotic agents, we can work towards improving the long-term outcomes for patients with PAD. It's a reminder that effective medical care involves not just treating symptoms, but also preventing future complications.
Date :
  1. Date Completed 2005-05-27
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

15674891

DOI: Digital Object Identifier

10.1002/14651858.CD002071.pub2

SNS
PICO Info
in preparation
Languages

English

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