Paper Details

  1. Home
  2. Paper Details

Study on serum and urinary cortisol levels of asthmatic patients after treatment with high dose inhaled beclomethasone dipropionate or budesonide.

Author: BansalS K, ChhabraS K, KaurCharanjeet

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Inhaled corticosteroids can be absorbed systemically, potentially leading to adverse effects. The study compared beclomethasone dipropionate (BDP) and budesonide (BUD) and found that they had similar effects on HPA axis suppression.
Paper Details　
Original Abstract of the Article :
The potential for long-term adverse effects from inhaled corticosteroids relates to their systemic absorption. With increasing use of high dose inhaled corticosteroids, there is need to establish whether similar doses of beclomethasone dipropionate (BDP) and budesonide (BUD) produce clinically impor...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/15832952

データ提供：米国国立医学図書館（NLM）

Inhaled Corticosteroids: A Balancing Act

This research investigates the potential for long-term adverse effects from inhaled corticosteroids, specifically focusing on their systemic absorption and impact on the hypothalamic-pituitary-adrenal (HPA) axis. The study compares two commonly used inhaled corticosteroids, beclomethasone dipropionate (BDP) and budesonide (BUD), at similar doses to determine if they produce clinically significant differences in side effects, particularly HPA axis suppression.

Finding the Right Dose: A Delicate Equilibrium

The study sheds light on the delicate balance between the therapeutic benefits and potential risks of inhaled corticosteroids. The findings suggest that careful consideration should be given to the dosage and type of inhaled corticosteroid prescribed, particularly for patients who may be at higher risk for HPA axis suppression. This highlights the need for ongoing monitoring and personalized treatment plans to ensure optimal outcomes for patients with asthma.

Navigating the Sandstorms of Asthma Treatment

Like navigating a sandstorm in the desert, managing asthma requires careful consideration of treatment options and potential side effects. This study provides valuable information for clinicians to guide their decision-making regarding inhaled corticosteroids, ensuring that patients receive effective treatment while minimizing potential risks.

Dr.Camel's Conclusion

This research offers important insights into the potential side effects of inhaled corticosteroids, particularly their impact on the HPA axis. The study underscores the need for a careful assessment of individual patient needs and a personalized approach to treatment, balancing the therapeutic benefits with the potential risks. By navigating the sandstorms of asthma treatment with a thoughtful and evidence-based approach, clinicians can help their patients achieve optimal health outcomes.
Date :
  1. Date Completed 2005-05-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

15832952

DOI: Digital Object Identifier

15832952

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.