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A comparative study of the haemodynamic effects of atropine and glycopyrrolate at induction of anaesthesia in children.

Author: BodeC O, DesaluI, KushimoO T

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effects of intravenous atropine and glycopyrrolate, anticholinergics, on haemodynamic changes and cardiac arrhythmias in children receiving halothane and suxamethonium. The study found that both atropine and glycopyrrolate prevented bradycardia but glycopyrrolate resulted in fewer cardiac arrhythmias.
Paper Details　
Original Abstract of the Article :
Bradycardia following administration of halothane and suxamethonium in children leads to reduced cardiac output, which can be prevented with prophylactic anticholinergics. Anticholinergics may result in tachycardia and arrhythmias. This study was designed to compare haemodynamic changes and incidenc...See full text at original site
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引用元：
https://doi.org/10.4314/wajm.v24i2.28179

データ提供：米国国立医学図書館（NLM）

Atropine vs. Glycopyrrolate: A Comparative Study of Haemodynamic Effects in Pediatric Anesthesia

The vast and intricate landscape of pediatric anesthesia often presents challenges, including the management of bradycardia. This study explores the haemodynamic effects of atropine and glycopyrrolate, two anticholinergic drugs commonly used to prevent bradycardia during pediatric anesthesia. The authors, like skilled anesthesiologists navigating the delicate balance of patient physiology, aim to understand the nuances of these drugs and their impact on young patients.

A Comparative Journey Through the Desert of Pediatric Anesthesia

The study compares the haemodynamic changes and incidence of cardiac arrhythmias following intravenous administration of atropine and glycopyrrolate in children undergoing anesthesia. The findings reveal subtle differences in the effects of these drugs, highlighting the importance of careful selection based on individual patient needs. It's like navigating different paths in the desert of pediatric anesthesia, each route leading to a unique destination with its own set of potential benefits and risks.

Navigating the Terrain of Pediatric Anesthesia Safely

This study provides valuable insights into the use of atropine and glycopyrrolate in pediatric anesthesia. The authors emphasize the need for careful consideration of the potential benefits and risks of these medications, tailoring treatment decisions to the specific needs of each child. It is like navigating a complex desert landscape, understanding the intricate balance of forces and choosing the most appropriate path for safe passage.

Dr. Camel's Conclusion

This study underscores the importance of understanding the nuances of drug effects in pediatric anesthesia. By carefully comparing the haemodynamic effects of atropine and glycopyrrolate, we can make informed decisions about medication choices, ensuring the safety and well-being of our young patients. It's a testament to the constant pursuit of knowledge and the careful navigation of the desert of pediatric anesthesia, always striving to improve patient outcomes.

Date :
  1. Date Completed 2005-10-11
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

16092310

DOI: Digital Object Identifier

10.4314/wajm.v24i2.28179

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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