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A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating.

Author: BaxterK, BurtonD D, CamilleriM, KimH J, StephensD, ThomfordeG, Vazquez RoqueM I, ZinsmeisterA R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

VSL#3 reduced flatulence scores and retarded colonic transit without altering bowel function in patients with irritable bowel syndrome (IBS) and bloating.
Paper Details　
Original Abstract of the Article :
AIM: To evaluate the effects of a combination probiotic on symptoms and colonic transit in patients with irritable bowel syndrome (IBS) and significant bloating. METHODS: Forty-eight patients with Rome II IBS were randomized in a parallel group, double-blind design to placebo or VSL# 3 twice daily ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-2982.2005.00695.x

データ提供：米国国立医学図書館（NLM）

Probiotics for Irritable Bowel Syndrome with Bloating

The world of irritable bowel syndrome (IBS) is like a desert of discomfort, where individuals grapple with a range of gastrointestinal symptoms, often accompanied by bloating. This study explores the potential of a probiotic combination, VSL#3, in alleviating symptoms and improving colonic transit in patients with IBS and significant bloating.

The Effects of Probiotics on IBS Symptoms

This study, like a carefully planned expedition across the desert, investigates the effects of VSL#3 on IBS symptoms using a randomized controlled trial. The findings, like a cool breeze in the desert, reveal that VSL#3 significantly reduced flatulence scores and slowed colonic transit in patients with IBS and bloating, suggesting a potential benefit for managing this challenging condition.

A New Oasis in the Desert of IBS

This study, like a well-placed oasis in the desert, offers a glimmer of hope for individuals with IBS. The findings suggest that probiotics may provide a natural and effective approach to managing IBS symptoms, offering relief from bloating and discomfort. It's a reminder that even in the most challenging of gastrointestinal landscapes, there's always potential for finding solutions.

Dr. Camel's Conclusion

This study underscores the potential of probiotics as a promising treatment option for IBS. By restoring the balance of gut microbiota, probiotics may help alleviate symptoms and improve quality of life for individuals battling this complex condition. It's a reminder that even in the most uncomfortable of deserts, there's always hope for a brighter future.

Date :
  1. Date Completed 2005-11-08
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

16185307

DOI: Digital Object Identifier

10.1111/j.1365-2982.2005.00695.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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