Empirical atypical coverage for inpatients with community-acquired pneumonia: systematic review of randomized controlled trials.

Author: LeiboviciLeonard, PaulMical, RobenshtokEyal, ShefetDaphna

Paper Details 
Original Abstract of the Article :
Current guidelines of empirical antibiotic treatment for inpatients with community-acquired pneumonia recommend antibiotics whose spectrum covers intracellular (atypical) pathogens. No sufficient evidence exists to support the necessity of such coverage, whereas limiting it may reduce toxic effects,...See full text at original site
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引用元:
https://doi.org/10.1001/archinte.165.17.1992

データ提供:米国国立医学図書館(NLM)

Atypical Pneumonia Treatment: Balancing Risks and Benefits

This study delves into the complex world of treating community-acquired pneumonia (CAP). Current guidelines often recommend broad-spectrum antibiotics that cover atypical pathogens, even though there's limited evidence supporting their necessity. This study systematically reviewed randomized controlled trials to assess the efficacy of empirically treating atypical pathogens in patients with CAP. The researchers aimed to determine if treating for atypical pathogens reduces mortality, improves clinical success, and has a positive impact on bacterial outcomes.

A Critical Look at Antibiotic Use

This study challenges the current practice of routinely treating CAP with broad-spectrum antibiotics that target atypical pathogens. The researchers found that there's limited evidence to support this approach, suggesting that a more targeted approach might be more appropriate.

Understanding Pneumonia

This research highlights the importance of careful consideration when choosing antibiotics for pneumonia. It’s crucial to consult with a healthcare professional for proper diagnosis and treatment.

Dr.Camel's Conclusion

This study delves into the complex world of treating community-acquired pneumonia (CAP). Current guidelines often recommend broad-spectrum antibiotics that cover atypical pathogens, even though there's limited evidence supporting their necessity. This study systematically reviewed randomized controlled trials to assess the efficacy of empirically treating atypical pathogens in patients with CAP. The researchers aimed to determine if treating for atypical pathogens reduces mortality, improves clinical success, and has a positive impact on bacterial outcomes. This study challenges the current practice of routinely treating CAP with broad-spectrum antibiotics that target atypical pathogens. The researchers found that there's limited evidence to support this approach, suggesting that a more targeted approach might be more appropriate.

Date :
  1. Date Completed 2005-11-01
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16186469

DOI: Digital Object Identifier

10.1001/archinte.165.17.1992

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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