Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women.

Author: BlissJ M, DawsonC K, GibsonL J, LawrenceD H

Paper Details 
Original Abstract of the Article :
Hormonal treatments for advanced or metastatic breast cancer, such as tamoxifen and the progestins megestrol acetate and medroxyprogesterone acetate, have been in use for many years. Aromatase inhibitors (AIs) are a class of compounds that systemically inhibit oestrogen synthesis in the peripheral t...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD003370.pub2

データ提供:米国国立医学図書館(NLM)

Aromatase Inhibitors: A New Era in Breast Cancer Treatment

This research focuses on [aromatase inhibitors (AIs)] for [the treatment of advanced breast cancer in postmenopausal women]. The study explores [the mechanism of action of AIs] and compares [the effectiveness and side effects of different generations of AIs]. The authors provide a comprehensive review of [clinical evidence] to assess [the role of AIs] in [the management of advanced breast cancer].

Aromatase Inhibitors: Effective and Well-Tolerated

The study demonstrates that [AIs are effective in reducing estrogen levels] and [inhibiting tumor growth] in postmenopausal women with advanced breast cancer. The researchers found that [third-generation AIs (anastrozole, exemestane, and letrozole)] are [well-tolerated] and have [similar efficacy] to other endocrine treatments. These findings highlight the importance of [considering AIs] as a [key therapeutic option] for advanced breast cancer.

Fighting Breast Cancer: A Multifaceted Approach

The fight against breast cancer is like a camel caravan traversing a vast and challenging desert. This research reveals that [AIs are a valuable tool] in the fight against this disease. The study emphasizes the need for [personalized treatment plans] that consider [individual patient factors] and [optimize treatment outcomes].

Dr.Camel's Conclusion

This research, like a camel caravan discovering a new and effective route through the desert of breast cancer treatment, highlights the importance of aromatase inhibitors in managing advanced breast cancer. It provides valuable information for clinicians and patients seeking effective and well-tolerated treatments.

Date :
  1. Date Completed 2007-05-08
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

17253488

DOI: Digital Object Identifier

10.1002/14651858.CD003370.pub2

SNS
PICO Info
in preparation
Languages

English

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