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Randomized comparison of a nicotine inhaler and bupropion for smoking cessation and relapse prevention.

Author: BernathAlbert, CroghanGary A, CroghanIvana T, DakhilShaker R, EbbertLarry P, FlynnKathleen A, GarneauStewart C, HurtRichard D, Le-LindqwisterNguyet A, LootsMary L, LoprinziCharles L, NovotnyPaul J, RowlandKendrith M, SloanJeff A, TschetterLoren K, WenderDonald B

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

Combining a nicotine inhaler and bupropion increased smoking abstinence rates compared to either treatment alone. At 3 months, 14% of nicotine inhaler users, 26% of bupropion users, and 34% of combined therapy users were abstinent.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare the combination of a nicotine inhaler and bupropion to either treatment alone for initiating smoking abstinence and relapse prevention. METHODS: Smokers were randomized to receive a nicotine inhaler, bupropion, or both for 3 months. At 3 months, smoking-abstinent study partici...See full text at original site
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引用元：
https://doi.org/10.4065/82.2.186

データ提供：米国国立医学図書館（NLM）

Quitting Smoking: A Journey Through the Desert of Addiction

Quitting smoking is a challenging journey, often likened to navigating a vast and unforgiving desert. This study examines the effectiveness of different approaches to smoking cessation, comparing the use of a nicotine inhaler, bupropion, and a combination of both. The researchers conducted a randomized controlled trial to evaluate the effectiveness of these treatments for initiating smoking abstinence and preventing relapse.

Navigating the Desert with Multiple Tools

The study found that combining a nicotine inhaler and bupropion resulted in higher smoking abstinence rates compared to either treatment alone. This suggests that combining different approaches can be more effective than relying on a single strategy. Imagine a traveler in a desert, equipped with a compass, map, and water bottle. Each tool serves a different purpose, and using them together increases the chance of reaching the desired destination. Similarly, using multiple tools to tackle smoking cessation might improve the chances of success.

Finding the Right Oasis

The researchers also observed that while the combination therapy was effective initially, it didn't prevent relapse in the long term. This highlights the need for ongoing support and strategies to prevent relapse after the initial cessation period. Finding a suitable oasis in the desert of addiction requires not only reaching the destination but also staying there. Continued effort and support are crucial for maintaining long-term abstinence.

Dr.Camel's Conclusion

This study sheds light on the complexity of smoking cessation and the importance of personalized approaches. Combining different strategies might be more effective than a single approach, but ongoing support is essential to navigate the challenges of maintaining abstinence in the long term. As we continue to explore the desert of addiction, we need to be mindful of the individual needs of each smoker and offer tailored support systems to help them reach their goals.

Date :
  1. Date Completed 2007-03-06
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

17290726

DOI: Digital Object Identifier

10.4065/82.2.186

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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