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Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring.

Author: DrenoBrigitte, JancoviciEliane, KatsambasAndreas, KhammariAmir, MorinetPierre, NoceraThérèse, PelfiniCarlo, PlantierDaniel, RibetVirginie

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A 0.1% retinaldehyde/6% glycolic acid (RALGA) cream was found to be effective in preventing and treating acne scarring in patients with moderate acne. In a double-blind vehicle-controlled study, patients using RALGA cream showed significant improvement in global scarring score, inflammatory lesions, and comedones after 28 days, compared to the vehicle group. After 3 months, the RALGA cream was significantly more efficient than the vehicle in reducing scarring due to erythema and hyperpigmentation improvement.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Acne often results in permanent, badly tolerated, difficult to treat scars. OBJECTIVE: To evaluate the efficacy and safety of a 0.1% retinaldehyde/6% glycolic acid (RALGA) cream at preventing and treating acne scarring in patients previously treated for moderate acne. METHODS: A double...See full text at original site
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引用元：
https://doi.org/10.1159/000099593

データ提供：米国国立医学図書館（NLM）

A Topical Treatment for Acne Scarring

This study delves into the world of dermatology, specifically focusing on acne scarring, a persistent problem for many. This research used a double-blind, controlled study to investigate the efficacy and safety of a cream containing 0.1% retinaldehyde and 6% glycolic acid (RALGA) in preventing and treating acne scarring. The researchers found that RALGA cream was more effective than a placebo in reducing scarring after three months, specifically in reducing redness and hyperpigmentation. This suggests that RALGA cream could be a valuable tool in managing acne scars.

A New Hope for Acne Scarring: The Potential of RALGA Cream

The study found that RALGA cream significantly improved global scarring scores, reducing both inflammatory lesions and comedones (blackheads) in patients with moderate acne. This indicates that RALGA cream could be a beneficial treatment option for individuals seeking to reduce the appearance of acne scars. The research suggests that the cream might work by reducing inflammation and hyperpigmentation, leading to a more even skin tone.

Beyond the Desert: The Importance of Scar Management

Acne scarring can have a significant impact on a person's self-esteem and quality of life. While the research shows promise for RALGA cream, it's important to remember that acne scarring is a complex condition, and treatment outcomes can vary. It's always essential to consult a dermatologist for personalized advice and treatment options.

Dr. Camel's Conclusion

This research suggests that RALGA cream could be a valuable tool for treating acne scarring. As with any medical treatment, it's crucial to talk to a qualified professional to determine if this treatment is right for you. Remember, even in the vast desert of skin conditions, there are oases of hope and effective treatments for those seeking to improve their skin's health and appearance.

Date :
  1. Date Completed 2007-05-17
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

17377389

DOI: Digital Object Identifier

10.1159/000099593

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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