The efficacy and safety of risperidone in the treatment of psychosis of Alzheimer's disease and mixed dementia: a meta-analysis of 4 placebo-controlled clinical trials.

Author: BrodatyHenry, GreenspanAndrew, KatzIra, MintzerJacobo, ZhuYoung, de DeynPeter-Paul

Paper Details 
Original Abstract of the Article :
BACKGROUND: Dementia typically includes behavioral and psychological symptoms of dementia (BPSD) as well as cognitive decline. Psychosis of Alzheimer's disease (AD) is a specific component of AD, characterized by delusions, misidentifications, and hallucinations. METHODS: This study is a meta-analy...See full text at original site
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引用元:
https://doi.org/10.1002/gps.1792

データ提供:米国国立医学図書館(NLM)

Risperidone: A Potential Treatment for Psychosis in Alzheimer's Disease

Alzheimer's disease (AD), a progressive neurodegenerative disorder, often leads to behavioral and psychological symptoms of dementia (BPSD), including psychosis. This research investigates the efficacy and safety of risperidone, an antipsychotic medication, in treating psychosis of AD.

Managing Psychosis: Exploring Treatment Options for AD

The researchers conducted a meta-analysis of four large placebo-controlled clinical trials and found that risperidone significantly improved psychotic symptoms in patients with AD compared to placebo. While risperidone was effective in reducing psychotic symptoms, it also increased the risk of extrapyramidal symptoms and somnolence. The research highlights the importance of carefully considering the potential benefits and risks of risperidone treatment for patients with AD.

Navigating the Challenges of Alzheimer's Disease

This research provides valuable insights into the treatment of psychosis in AD. It underscores the need for individualized treatment plans that consider the specific needs and risks of each patient. Close monitoring and careful management are essential to ensure that the benefits of risperidone outweigh the potential side effects.

Dr. Camel's Conclusion

Risperidone, like a skilled navigator guiding a caravan through the desert of Alzheimer's disease, offers potential relief from the debilitating symptoms of psychosis. However, like any journey through the desert, it's crucial to approach this treatment with caution and seek guidance from a healthcare professional to ensure a safe and successful path.
Date :
  1. Date Completed 2007-12-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17471598

DOI: Digital Object Identifier

10.1002/gps.1792

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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