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[Fixed drug combination of ACE inhibitor plus diuretic. Results of an open multicenter study for the treatment of hypertension].

Author: LederleR M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

A fixed combination of captopril and hydrochlorothiazide (Capozide) was effective in lowering blood pressure in patients with mild-to-moderate hypertension. In a study of 34,976 patients, 87.2% achieved a significant reduction in blood pressure after 8 weeks of treatment. The most common side effect was mild and occurred in 7.4% of patients.
Paper Details　
Original Abstract of the Article :
An open multicenter trial involving 7,232 participating physicians, was performed to assess the anti-hypertensive efficacy and tolerance of a fixed combination of captopril and hydrochlorothiazide (Capozide) given once daily to 34,976 patients (mean age 58.5 +/- 11.4 years) with mild-to-moderate hyp...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1761267

データ提供：米国国立医学図書館（NLM）

Fixed Drug Combination for Hypertension: A Comprehensive Multicenter Study

This research delves into the treatment of hypertension, a condition that affects millions worldwide, much like a vast desert where high blood pressure can be a silent and dangerous threat. The study investigated the efficacy and safety of a fixed combination of captopril and hydrochlorothiazide (Capozide) for treating mild-to-moderate hypertension. The results show that Capozide, a potent combination of drugs, was highly effective in lowering blood pressure and was generally well-tolerated.

Capozide: A Promising Approach to Hypertension Management

This study demonstrates the effectiveness of Capozide in managing hypertension, offering a promising approach for controlling blood pressure. The study found that Capozide was effective in lowering blood pressure and was well-tolerated by most patients. This information can be valuable in guiding treatment decisions for individuals with hypertension.

Managing Hypertension for a Healthier Life

It's important to be aware of your blood pressure and work with your healthcare provider to manage hypertension effectively. Lifestyle modifications, such as adopting a healthy diet, regular exercise, and stress management techniques, can play a crucial role in controlling blood pressure.

Dr.Camel's Conclusion

This research highlights the effectiveness and safety of a fixed combination of captopril and hydrochlorothiazide (Capozide) in treating mild-to-moderate hypertension. It offers valuable insights into the management of this common condition and suggests that this drug combination may be a suitable treatment option for many individuals.
Date :
  1. Date Completed 1992-02-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1761267

DOI: Digital Object Identifier

1761267

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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