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Results of a phase III, 8-week, multicenter, prospective, randomized, double-blind, parallel-group clinical trial to assess the effects of amlodipine camsylate versus amlodipine besylate in Korean adults with mild to moderate hypertension.

Author: , AhnYoung-Keun, ChungWook-Sung, KimHyo-Soo, KimIn-Jae, KimJae-Joong, KimSang-Hyun, KimYoung-Dae, LeeJe-Won, LimDo-Sun, OnYoung-Keun, ParkJung-Bae, SeoHong-Seok, ShinEak-Kyun, YangJu-Young, YoonMyeong-Ho

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Amlodipine camsylate, a newer formulation, showed similar effectiveness to amlodipine besylate in lowering blood pressure in patients with hypertension.
Paper Details　
Original Abstract of the Article :
Amlodipine besylate has been used in Korea for the treatment of hypertension for >17 years, with well-established efficacy and tolerability. Amlodipine camsylate is a newer formulation developed for generic use. It has been assessed in terms of physical stability and pharmacokinetic and pharmacodyna...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinthera.2007.09.018

データ提供：米国国立医学図書館（NLM）

Comparing Amlodipine Camsylate and Amlodipine Besylate for Hypertension

Amlodipine is a widely used medication for treating hypertension (high blood pressure). This study compares the effectiveness and tolerability of two amlodipine formulations: amlodipine camsylate and amlodipine besylate, in Korean adults with mild to moderate hypertension. The researchers found that both formulations were effective in lowering blood pressure, with no significant difference in efficacy or tolerability between the two.

A Tale of Two Formulations: Exploring the Effectiveness of Amlodipine

This research delves into the nuances of amlodipine formulations, highlighting the importance of understanding how different forms of a medication may affect its effectiveness. It's like exploring different routes through a desert, each offering a unique experience. This study suggests that both amlodipine camsylate and amlodipine besylate can be effective treatment options for hypertension.

Navigating the Desert of Hypertension: Choosing the Right Path

This study provides valuable information for patients and doctors seeking the best treatment for hypertension. It's like having a map of the desert, guiding us to the most effective and safe path. This study suggests that both amlodipine camsylate and amlodipine besylate can be effective treatment options for hypertension.

Dr. Camel's Conclusion

This study provides reassuring information for patients and doctors seeking effective treatment for hypertension. It's like finding a reliable oasis in the desert, offering a safe and effective solution for managing blood pressure. The research suggests that both amlodipine camsylate and amlodipine besylate can be effective treatment options for hypertension.

Date :
  1. Date Completed 2008-01-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18035192

DOI: Digital Object Identifier

10.1016/j.clinthera.2007.09.018

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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