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Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial.
Author: , BaumMichael, BuzdarAman, CuzickJack, ForbesJohn F, HowellAnthony, TobiasJeffrey S
Original Abstract of the Article :
Little data exist on whether efficacy benefits or side-effects persist after 5 years of adjuvant treatment with an aromatase inhibitor. We aimed to study long-term outcomes in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial that compares anastrozole with tamoxifen after a median follow...See full text at original site
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引用元:
https://doi.org/10.1016/S1470-2045(07)70385-6
データ提供:米国国立医学図書館(NLM)
Long-Term Outcomes of Anastrozole vs. Tamoxifen for Early-Stage Breast Cancer
Breast cancer is a prevalent disease, and adjuvant therapy, administered after surgery, plays a crucial role in preventing recurrence. This study, a 100-month analysis of the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial, investigates the long-term outcomes of anastrozole and tamoxifen as adjuvant treatments for early-stage breast cancer. The researchers compared the long-term efficacy and side effects of these two medications, providing valuable insights into their long-term impact on breast cancer patients. The study found that anastrozole, an aromatase inhibitor, provided a significant advantage in terms of disease-free survival compared to tamoxifen, an anti-estrogen medication. However, the study also noted that the benefits of anastrozole, particularly in terms of disease-free survival, remained evident even after 5 years of treatment. This research provides crucial information for guiding treatment decisions and optimizing long-term outcomes for patients with early-stage breast cancer.Long-Term Benefits of Anastrozole: A Promising Strategy for Breast Cancer
This study provides strong evidence supporting the long-term efficacy of anastrozole as an adjuvant treatment for early-stage breast cancer. The continued benefits of anastrozole, even after 5 years of treatment, make it a potentially valuable option for minimizing recurrence and improving long-term outcomes for patients. This research highlights the importance of considering long-term implications when choosing adjuvant therapies for breast cancer.Navigating the Landscape of Breast Cancer Treatment
Breast cancer, like a vast desert landscape, presents numerous challenges and requires a personalized approach to treatment. This study underscores the importance of considering the long-term implications of treatment options, aiming to optimize outcomes for patients and minimize the risk of recurrence. Understanding the nuances of breast cancer treatment is crucial for making informed decisions about therapy and improving the lives of those affected.Dr.Camel's Conclusion
Breast cancer treatment, like a journey across the desert, requires careful planning and navigation. This research provides a valuable roadmap for choosing long-term adjuvant therapies, highlighting the potential benefits of anastrozole in minimizing recurrence and improving the long-term outlook for breast cancer patients. As we continue to explore the complexities of breast cancer, we can develop even more effective strategies for combating this challenging disease and improving the lives of those affected.Date :
- Date Completed 2008-01-17
- Date Revised 2022-04-08
Further Info :
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