Impact of disease risk on efficacy of matched related bone marrow transplantation for pediatric acute myeloid leukemia: the Children's Oncology Group.

Author: , AlonzoTodd A, BectonDavid, GerbingRobert B, HoranJohn T, LangeBeverly J, LymanGary H, RavindranathYaddanapudi, SmithFranklin O, WoodsWilliam G

Paper Details 
Original Abstract of the Article :
There is considerable variation in the use of HLA-matched related bone marrow transplantation (BMT) for the treatment of pediatric patients with newly diagnosed acute myeloid leukemia (AML). Some oncologists have argued that BMT should be offered to most patients in first complete remission (CR). Ot...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645105/

データ提供:米国国立医学図書館(NLM)

Matched Related Bone Marrow Transplantation: A Valuable Tool for Pediatric Acute Myeloid Leukemia

Pediatric acute myeloid leukemia (AML) is a serious and often life-threatening cancer. This study, published in [Journal Name], investigates the efficacy of HLA-matched related bone marrow transplantation (BMT) in treating pediatric patients with newly diagnosed AML. The researchers analyzed data from a large cohort study (Children's Oncology Group) to determine the impact of disease risk on the effectiveness of BMT.

BMT: A Potentially Life-Saving Treatment for High-Risk AML

The study found that BMT was associated with improved outcomes for pediatric patients with high-risk AML. The researchers concluded that BMT should be considered as a treatment option for these patients, potentially offering a chance for long-term remission and survival.

Personalizing Treatment: Balancing Risks and Benefits

The study highlights the importance of carefully weighing the risks and benefits of BMT for each individual patient. The authors suggest that BMT may be particularly beneficial for patients with high-risk AML, who may have a higher likelihood of relapse if treated with chemotherapy alone.

Dr.Camel's Conclusion

Like a camel navigating the harsh desert of cancer treatment, this study provides valuable insights into the potential benefits of BMT for pediatric patients with high-risk AML. The researchers have highlighted the importance of personalized treatment approaches, considering both the risks and benefits of BMT for each individual patient. The findings offer hope for those facing this challenging diagnosis, providing evidence-based support for the use of BMT as a potentially life-saving treatment option.

Date :
  1. Date Completed 2009-01-06
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

18955460

DOI: Digital Object Identifier

PMC2645105

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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